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XCL1 and CXCL14
Number of citations of the paper that reports this interaction (PubMedID
28381538
)
37
Data Source:
BioGRID
(pull down)
XCL1
CXCL14
Description
X-C motif chemokine ligand 1
C-X-C motif chemokine ligand 14
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Extracellular Space
Golgi Apparatus
Molecular Function
Protein Binding
Chemokine Activity
Chemokine Receptor Binding
Protein Homodimerization Activity
CCR Chemokine Receptor Binding
Protein Binding
Chemokine Activity
Biological Process
Positive Regulation Of T Cell Mediated Cytotoxicity
Monocyte Chemotaxis
Positive Regulation Of Leukocyte Chemotaxis
Negative Regulation Of T Cell Cytokine Production
Positive Regulation Of T Cell Cytokine Production
Negative Regulation Of T-helper 1 Type Immune Response
Inflammatory Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Response To Virus
Positive Regulation Of T Cell Chemotaxis
Neutrophil Chemotaxis
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-10 Production
Mature Natural Killer Cell Chemotaxis
Negative Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of GTPase Activity
Negative Regulation Of Transcription, DNA-templated
Lymphocyte Chemotaxis
Regulation Of Inflammatory Response
Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Interleukin-4
Cellular Response To Tumor Necrosis Factor
Cellular Response To Transforming Growth Factor Beta Stimulus
Positive Regulation Of Transforming Growth Factor Beta Production
Positive Regulation Of Granzyme B Production
Positive Regulation Of Neutrophil Chemotaxis
Positive Regulation Of Thymocyte Migration
Positive Regulation Of Natural Killer Cell Chemotaxis
Positive Regulation Of Granzyme A Production
Negative Regulation Of T-helper 1 Cell Activation
Positive Regulation Of B Cell Chemotaxis
Positive Regulation Of T-helper 2 Cell Cytokine Production
Positive Regulation Of T-helper 1 Cell Cytokine Production
Positive Regulation Of Immunoglobulin Production In Mucosal Tissue
Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Positive Regulation Of CD8-positive, Alpha-beta T Cell Proliferation
Chemotaxis
Signal Transduction
Cell-cell Signaling
Cell Chemotaxis
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways
Chemokine receptors bind chemokines
G alpha (q) signalling events
Drugs
Diseases
GWAS
Blood protein levels (
30072576
29875488
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Metabolite levels (
23823483
)
Age at smoking initiation in chronic obstructive pulmonary disease (
21685187
)
Cerebrospinal fluid p-tau levels in Alzheimer's disease dementia (
29274321
)
Cerebrospinal fluid t-tau levels (
29274321
)
Interacting Genes
21 interacting genes:
CCL11
CCL13
CCL21
CCL24
CCL26
CCL28
CCL5
CXCL10
CXCL11
CXCL12
CXCL14
CXCL17
CXCL2
CXCL9
FBLN5
KRTAP10-3
PF4
PF4V1
TNFSF18
VCAN
XCR1
28 interacting genes:
APP
CCL11
CCL13
CCL21
CCL26
CCL28
CCL5
CXCL10
CXCL11
CXCL12
CXCL17
CXCL2
CXCL5
CXCL9
F2R
GPR85
JMJD6
KLRC1
LMNA
PF4
PPBP
REL
ROBO3
SLAMF6
TEX11
TNFRSF10C
TRIM23
XCL1
Entrez ID
6375
9547
HPRD ID
02595
16049
Ensembl ID
ENSG00000143184
ENSG00000145824
Uniprot IDs
P47992
O95715
PDB IDs
1J8I
1J9O
2HDM
2JP1
2N54
2NYZ
2HDL
Enriched GO Terms of Interacting Partners
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