BICD1 and RAB6A

Number of citations of the paper that reports this interaction (PubMedID 12447383)
137

Data Source:
BioGRID (pull down)
HPRD (in vitro, two hybrid, in vivo)

		BICD1	RAB6A
Description		BICD cargo adaptor 1	RAB6A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Centrosome Cytosol Cytoskeleton Cytoplasmic Microtubule Membrane Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm Secretory Vesicle	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Extracellular Exosome Endosome To Plasma Membrane Transport Vesicle
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Anchor Activity Protein Kinase Binding Small GTPase Binding Proteinase Activated Receptor Binding Dynactin Binding Dynein Intermediate Chain Binding Dynein Complex Binding	GTPase Activity Protein Binding GTP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	RNA Processing Intracellular MRNA Localization Anatomical Structure Morphogenesis Viral Process Protein Localization To Organelle Stress Granule Assembly Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Microtubule Cytoskeleton Organization Minus-end-directed Organelle Transport Along Microtubule Microtubule Anchoring At Microtubule Organizing Center Negative Regulation Of Phospholipase C Activity Regulation Of Proteinase Activated Receptor Activity Negative Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Localization To Centrosome	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Peptidyl-cysteine Methylation Antigen Processing And Presentation Protein Localization To Golgi Apparatus Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Minus-end-directed Organelle Transport Along Microtubule
Pathways		COPI-independent Golgi-to-ER retrograde traffic	Pre-NOTCH Processing in Golgi Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic Retrograde transport at the Trans-Golgi-Network TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Emphysema-related traits ( 20709820) Fourth ventricle volume ( 31530798) Intralaminar thalamic nuclei volume ( 34006833) Left ventricular mass x antihypertensive treatment interaction ( 31407531) Normalized brain volume ( 19010793) Obesity-related traits ( 23251661) Pancreatic cancer ( 20686608) Parkinson's disease ( 32201043)	Dimensional psychopathology (Cognitive) ( 29496196) Obesity-related traits ( 23251661)
Interacting Genes		13 interacting genes: ALPI CPNE4 DCTN1 DCTN2 DISC1 DYNC1I1 FXR1 GSK3A GSK3B MAPK14 NIN RAB6A STAT3	22 interacting genes: BICD1 BICD2 CHM CHML DCTN1 ERC1 FKBP2 GDI1 GOLGA1 GOLGA2 GOLGA4 GORAB KIF20A OCRL PMM1 RAB7A RABAC1 RABGAP1 RABGGTB SHANK2 SYTL5 TMF1
Entrez ID		636	5870
HPRD ID		03730	01543
Ensembl ID		ENSG00000151746	ENSG00000175582
Uniprot IDs		Q96G01	A0A024R5H8 A0A024R5J5 P20340 Q53ET8
PDB IDs			1YZQ 2GIL 3BBP 3CWZ 4DKX 5LEF
Enriched GO Terms of Interacting Partners?
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