SCNN1A and SCNN1B

Number of citations of the paper that reports this interaction (PubMedID 8986818)
117

Data Source:
HPRD (in vivo)

		SCNN1A	SCNN1B
Description		sodium channel epithelial 1 subunit alpha	sodium channel epithelial 1 subunit beta
Image
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Motile Cilium Sodium Channel Complex Ciliary Membrane Extracellular Exosome Sperm Principal Piece	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Membrane Sodium Channel Complex Extracellular Exosome Plasma Membrane Protein Complex
	Molecular Function	Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding	Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding
	Biological Process	Sodium Ion Transmembrane Transport Multicellular Organismal Water Homeostasis Response To Stimulus Sensory Perception Of Taste Sodium Ion Homeostasis	Leukocyte Activation Involved In Inflammatory Response Neutrophil Activation Involved In Immune Response Sodium Ion Transport Excretion Response To Xenobiotic Stimulus Gene Expression Artery Smooth Muscle Contraction Response To Food Aldosterone Metabolic Process Erythrocyte Homeostasis Multicellular Organism Growth Sodium Ion Transmembrane Transport Epithelial Fluid Transport Multicellular Organismal Water Homeostasis Sensory Perception Of Taste Potassium Ion Homeostasis Sodium Ion Homeostasis Mucus Secretion Neutrophil-mediated Killing Of Bacterium Urea Homeostasis Cellular Response To Aldosterone
Pathways		Stimuli-sensing channels	Stimuli-sensing channels
Drugs		Triamterene Amiloride	Triamterene Amiloride
Diseases
GWAS		Adverse response to drug ( 30420678) Alopecia areata ( 25608926) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Obesity (early onset extreme) ( 23563609) Primary biliary cirrhosis ( 22961000) Spleen volume ( 34128465)	Kidney stones ( 31729369)
Interacting Genes		18 interacting genes: COMMD10 CSNK2A1 EPN1 HECW1 ITCH NEDD4 NEDD4L NPC2 SCNN1B SCNN1G SERP1 SNX3 STX1A TSG101 UBE2I USP10 WWP1 WWP2	14 interacting genes: ANK3 CNTN1 COMMD10 EPN1 HECW1 ITCH NEDD4 NEDD4L NFASC SCNN1A SCNN1D SCNN1G STX1A WWP2
Entrez ID		6337	6338
HPRD ID		02575	02861
Ensembl ID		ENSG00000111319	ENSG00000168447
Uniprot IDs		P37088	B2R812 P51168
PDB IDs		2M3O 6BQN 6WTH	6BQN 6WTH
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?