SAT1 and RPLP1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SAT1	RPLP1
Description		spermidine/spermine N1-acetyltransferase 1	ribosomal protein lateral stalk subunit P1
Image
GO Annotations	Cellular Component	Cytosol	Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Cytosolic Ribosome
	Molecular Function	Diamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Spermidine Binding Identical Protein Binding	Structural Constituent Of Ribosome Protein Binding Protein Kinase Activator Activity Ribonucleoprotein Complex Binding
	Biological Process	Angiogenesis Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation	Cytoplasmic Translation Translation Translational Elongation Activation Of Protein Kinase Activity
Pathways		Interconversion of polyamines	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases
GWAS		Shoulder impingement or rotator cuff tear ( 33482370)	Chronic lymphocytic leukemia ( 28165464 24292274 23770605) Male-pattern baldness ( 27182965) Non-response to citalopram or escitalopram and depression ( 27622933)
Interacting Genes		98 interacting genes: ABCB8 ABHD15 APLP1 B4GALT3 BHLHA9 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CDC42EP1 CEP126 CHD3 COPS6 COX6C CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DIPK1B DMRT3 DNPEP EEF1G EIF3D EPHB6 ERG28 EVA1A FAM156A FAM228A FAM86C1P FH FTSJ3 FUNDC2 GAS2L2 GBP2 GDF9 HIF1A HOXB6 HOXB9 HSPB1 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KHDC4 LHX3 LNX1 LRIF1 LUC7L2 LYRM7 MED31 MEOX2 MRPL12 MRPL9 MTA1 MYPOP NIF3L1 NMRK2 NTAQ1 PLGRKT PRDX2 PSMA1 PTN RACK1 RBM17 RBM48 REL RELA RPLP1 RPP25 SARAF SAT2 SEPHS1 SETDB1 SNAI2 TACO1 TCF25 TEAD4 TEX43 TLE1 TLE5 TNNI1 TP53 TP53TG1 TSC22D4 TUBB2A TXN2 UBE2D3 UNC119 USHBP1 UTP14A VASP VKORC1 ZHX1	36 interacting genes: ANKRD13B ARF6 ASCC2 ATP5MF BRD7 C11orf58 C15orf39 CDIPT CDK2AP2 CLIC1 CSNK2A1 EEF1A1 GEMIN7 GSK3B LRIF1 MAP1LC3B MPC2 NSF NUDT21 NUDT3 PDCD4 PFDN1 PPP2CB PTN RCHY1 RPA2 RPLP2 RPS6KA6 SAT1 SGO1 SUOX TAB1 TPT1 TUBB2A UBE2D3 XRCC6
Entrez ID		6303	6176
HPRD ID		02431	01611
Ensembl ID		ENSG00000130066	ENSG00000137818
Uniprot IDs		A0A384NQ10 P21673	A0A024R608 P05386
PDB IDs		2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV	2LBF 4BEH 4V6X
Enriched GO Terms of Interacting Partners?
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