S100A10 and FSHR

Number of citations of the paper that reports this interaction (PubMedID 15196694)
17

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		S100A10	FSHR
Description		S100 calcium binding protein A10	follicle stimulating hormone receptor
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Extrinsic Component Of Plasma Membrane Membrane Raft Collagen-containing Extracellular Matrix Extracellular Exosome AnxA2-p11 Complex	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Receptor Complex
	Molecular Function	Calcium Ion Binding Protein Binding Lipid Binding Protein Homodimerization Activity Transmembrane Transporter Binding Calcium-dependent Protein Binding	Follicle-stimulating Hormone Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity
	Biological Process	Membrane Raft Assembly Vesicle Budding From Membrane Response To Xenobiotic Stimulus Positive Regulation Of GTPase Activity Positive Regulation Of Binding Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Substrate Adhesion-dependent Cell Spreading	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Spermatogenesis Female Gamete Generation Gonad Development Male Gonad Development Female Gonad Development Hormone-mediated Signaling Pathway Regulation Of Protein Kinase A Signaling Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Follicle-stimulating Hormone Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Follicle-stimulating Hormone Stimulus
Pathways		Dissolution of Fibrin Clot	Hormone ligand-binding receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs		Phenethyl Isothiocyanate	Menotropins Follitropin Urofollitropin Choriogonadotropin alfa Suramin Corifollitropin alfa
Diseases
GWAS		Asthma ( 31619474) Diverticular disease ( 30177863) Serum metabolite levels ( 33031748) Urinary metabolite levels in chronic kidney disease ( 29545352) Urinary metabolite ratios in chronic kidney disease ( 29545352)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide) ( 23648065) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Chronotype ( 30696823) Daytime nap ( 33568662) Depressive symptoms (SSRI exposure interaction) ( 25649181) Erectile dysfunction and prostate cancer treatment ( 20932654) HDL cholesterol levels in HIV infection ( 33109212) Laterality in neovascular age-related macular degeneration ( 28775256) Lean body mass ( 28552196) Low density lipoprotein cholesterol levels ( 30498476) Lung cancer in ever smokers ( 28604730) Metabolite levels ( 23823483) Morning person ( 30696823) Plasma anti-thyroglobulin levels ( 29678681) Polycystic ovary syndrome ( 22885925 21151128) Radiation response ( 20923822) Recurrent major depressive disorder ( 34099189) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
Interacting Genes		21 interacting genes: ANXA2 ANXA7 BAD CDK16 COPS6 CTSB ERBB3 FSHR KCNK3 MLKL NANOS2 PLA2G4C PLG S100A3 S100Z SETDB1 SUMO2 TRPV5 TRPV6 USP2 ZGPAT	20 interacting genes: AKT2 APPL1 ARR3 CANX CBX5 CGA FSHB GRK2 GRK4 GRK6 MT-RNR2 RPS27A S100A10 TOP1 TUG1 UBA52 UBB UBC YWHAQ ZBTB16
Entrez ID		6281	2492
HPRD ID		00232	00639
Ensembl ID		ENSG00000197747	ENSG00000170820
Uniprot IDs		P60903	A0A1D5RMN4 P23945
PDB IDs		1A4P 1BT6 4DRW 4FTG 4HRE 4HRG 4HRH	1XUN 1XWD 4AY9 4MQW
Enriched GO Terms of Interacting Partners?
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