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RPL13 and RELA
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
136
Data Source:
BioGRID
(two hybrid)
RPL13
RELA
Description
ribosomal protein L13
RELA proto-oncogene, NF-kB subunit
Image
GO Annotations
Cellular Component
Nucleus
Nucleolus
Endoplasmic Reticulum
Cytosol
Membrane
Cytosolic Large Ribosomal Subunit
Cytosolic Ribosome
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Nucleolus
Cytoplasm
Cytosol
NF-kappaB P50/p65 Complex
Glutamatergic Synapse
Molecular Function
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
Transcription Cis-regulatory Region Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Transcription Coactivator Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Enzyme Binding
Protein Kinase Binding
Chromatin DNA Binding
Ubiquitin Protein Ligase Binding
Peptide Binding
Phosphate Ion Binding
Identical Protein Binding
Protein Homodimerization Activity
Actinin Binding
Histone Deacetylase Binding
Protein-containing Complex Binding
Protein N-terminus Binding
NF-kappaB Binding
Ankyrin Repeat Binding
General Transcription Initiation Factor Binding
DNA-binding Transcription Factor Binding
Biological Process
Blastocyst Development
Cytoplasmic Translation
Translation
Bone Development
Negative Regulation Of Transcription By RNA Polymerase II
Liver Development
Hair Follicle Development
Acetaldehyde Metabolic Process
Chromatin Organization
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Inflammatory Response
Cellular Defense Response
I-kappaB Kinase/NF-kappaB Signaling
Aging
Positive Regulation Of Cell Population Proliferation
Response To Xenobiotic Stimulus
Animal Organ Morphogenesis
Response To Organic Substance
Response To UV-B
Positive Regulation Of Schwann Cell Differentiation
Cytokine-mediated Signaling Pathway
Response To Muramyl Dipeptide
Response To Progesterone
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-8 Production
Response To Insulin
Tumor Necrosis Factor-mediated Signaling Pathway
Negative Regulation Of Protein Sumoylation
Cellular Response To Stress
Response To Cobalamin
Response To Cytokine
Cellular Response To Hepatocyte Growth Factor Stimulus
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Response To Muscle Stretch
NIK/NF-kappaB Signaling
Negative Regulation Of Protein Catabolic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Amino Acid
Response To Morphine
Regulation Of DNA-templated Transcription In Response To Stress
Innate Immune Response
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Insulin Receptor Signaling Pathway
Regulation Of Inflammatory Response
Positive Regulation Of T Cell Receptor Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Response To CAMP
Defense Response To Virus
Cellular Response To Hydrogen Peroxide
Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway
Interleukin-1-mediated Signaling Pathway
Response To Interleukin-1
Cellular Response To Lipopolysaccharide
Cellular Response To Lipoteichoic Acid
Cellular Response To Peptidoglycan
Cellular Response To Nicotine
Cellular Response To Interleukin-1
Cellular Response To Interleukin-6
Cellular Response To Tumor Necrosis Factor
Postsynapse To Nucleus Signaling Pathway
Regulation Of NIK/NF-kappaB Signaling
Negative Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus
Positive Regulation Of Amyloid-beta Formation
Negative Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Cellular Response To Angiotensin
Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Positive Regulation Of MiRNA Metabolic Process
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Activation of NF-kappaB in B cells
RIP-mediated NFkB activation via ZBP1
Regulated proteolysis of p75NTR
Downstream TCR signaling
NF-kB is activated and signals survival
Senescence-Associated Secretory Phenotype (SASP)
FCERI mediated NF-kB activation
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
PKMTs methylate histone lysines
Transcriptional regulation of white adipocyte differentiation
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
Interleukin-1 processing
SUMOylation of immune response proteins
IkBA variant leads to EDA-ID
Dectin-1 mediated noncanonical NF-kB signaling
CLEC7A (Dectin-1) signaling
CD209 (DC-SIGN) signaling
CLEC7A/inflammasome pathway
The NLRP3 inflammasome
Transcriptional Regulation by VENTX
Interleukin-1 signaling
TRAF6 mediated NF-kB activation
Purinergic signaling in leishmaniasis infection
Drugs
Dimethyl fumarate
SC-236
Diseases
GWAS
Hair morphology traits (
30166351
)
Acne (severe) (
24927181
)
Asthma (
31619474
)
Diastolic blood pressure (cigarette smoking interaction) (
29455858
)
Inflammatory bowel disease (
23128233
)
LDL cholesterol levels (
32203549
)
Sensation seeking (
30718321
)
Systolic blood pressure (cigarette smoking interaction) (
29455858
)
Urate levels (
31985003
31578528
)
Interacting Genes
23 interacting genes:
ANXA7
CDK12
CEP70
CSNK2A1
CSNK2B
DAXX
DUX4
ERCC6
HSBP1
ILK
IPO5
MAP2K3
MAPKAPK5
OGT
PTEN
RAD21
RELA
SMN1
SPP1
SRPK2
TERF2
TK1
UPF2
213 interacting genes:
AATF
ACTL6A
AGO1
AHR
AKAP8
APBA2
AR
ARNT
ASB9
AURKA
BANP
BATF2
BCL3
BRCA1
BRMS1
BTK
BTRC
C1QB
CALM1
CAMK4
CARM1
CCL5
CCND2
CDC34
CDK9
CEBPB
CEBPD
CHEK1
CHUK
CNNM3
COL2A1
COMMD1
CREBBP
CSNK1G1
CSNK2A1
CSNK2A2
DDC
DDX1
DHX9
DNAJA3
DNMT3L
DPF2
ECSIT
EEF1D
EGR1
EP300
EPHA2
ESR1
ETHE1
EZH2
FAF1
FBP1
FKBP11
FOS
FUS
GLIS1
GOPC
GTF2B
HDAC1
HDAC2
HDAC3
HEXIM1
HMGA2
HMGB1
HSPA4
IGF1R
IKBKB
IKBKE
IKBKG
ING4
IRAK1BP1
IRF1
IRF2
IRF3
IRF8
IRF9
ISL1
ITGB3BP
JUN
KAT2A
KAT2B
KAT5
KDM2A
KEAP1
KPNA2
LATS2
LMO2
MAP2K6
MAP3K7
MAP3K8
MAP4K2
MAPK10
MAPK14
MED15
MED23
MED7
MEN1
MEOX2
MKRN2
MST1R
MTPN
MX1
MYC
NCOA3
NCOA6
NCOR2
NFE2L2
NFIC
NFKB1
NFKB2
NFKBIA
NFKBIB
NFKBIE
NKRF
NKX2-1
NOTCH1
NPM1
NR3C1
PARP1
PDCD11
PGA5
PGR
PIAS1
PIAS3
PIK3CA
PIN1
PKM
PLA2G4A
PLK1
PML
POU2F1
POU6F2
PPARA
PPP1CA
PPP1R13L
PPP2CA
PPP2CB
PPP2R1B
PPP4C
PRKACA
PRKCZ
PRMT1
PRTN3
PSMD10
RAB11A
RAD51
RASSF1
RBM4
REL
RELB
REPS2
RFC1
RIOK2
RNASE1
RNF25
RPL13
RPL23
RPS3
RPS6KA5
RTN4IP1
RXRA
SAT1
SETD7
SIN3A
SIRT1
SLC3A2
SMAD3
SMAD4
SNIP1
SNRNP70
SOCS1
SOCS6
SORD
SP1
SRF
STAT1
STAT3
STAT6
SUOX
TAF1
TAF11
TAF4B
TAF6
TAF9
TBK1
TBP
TCAP
TCF4
TERT
TGM2
TLE5
TNIP2
TP53
TP53BP1
TP53BP2
TRIB3
TRIM55
TRIM63
TRIP4
TSC22D3
TWIST1
UBE2C
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2H
UBE2L3
UNC5CL
USF2
USP7
ZBTB7A
ZBTB7B
Entrez ID
6137
5970
HPRD ID
06428
01241
Ensembl ID
ENSG00000167526
ENSG00000173039
Uniprot IDs
A8K4C8
P26373
A0A087X0W8
Q04206
PDB IDs
4UG0
4V6X
5AJ0
5LKS
5T2C
6EK0
6IP5
6IP6
6IP8
6LQM
6LSR
6LSS
6LU8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6W6L
6XA1
6Y0G
6Y2L
6Y57
6Y6X
6Z6L
6Z6M
6Z6N
6ZM7
6ZME
6ZMI
6ZMO
7BHP
1NFI
2LSP
2O61
3GUT
3QXY
3RC0
4KV1
4KV4
5U4K
5URN
6NV2
6QHL
6QHM
6YOW
6YOX
6YOY
6YP2
6YP3
6YP8
6YPL
6YPY
6YQ2
Enriched GO Terms of Interacting Partners
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