RFC5 and TASOR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RFC5	TASOR2
Description		replication factor C subunit 5	transcription activation suppressor family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm DNA Replication Factor C Complex Ctf18 RFC-like Complex	Nucleoplasm Cytosol
	Molecular Function	DNA Binding DNA Clamp Loader Activity Protein Binding ATP Binding Single-stranded DNA Helicase Activity Enzyme Binding	Protein Binding
	Biological Process	DNA Replication DNA-dependent DNA Replication DNA Repair DNA Duplex Unwinding Positive Regulation Of DNA-directed DNA Polymerase Activity
Pathways		Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Polymerase switching on the C-strand of the telomere Activation of ATR in response to replication stress PCNA-Dependent Long Patch Base Excision Repair Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Regulation of TP53 Activity through Phosphorylation Polymerase switching G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Chronic rhinosinusitis ( 33393196) Metabolite levels ( 23823483) Neurociticism ( 29500382) Obesity-related traits ( 23251661) Physiological traits ( 31902109)
Interacting Genes		36 interacting genes: ARID5A BIRC2 CCNC CHTF18 COPS6 DAPK1 DDIT4L DYNLL1 EEF1A1 EML2 EXOSC8 FAM166B KRT34 LMO3 LRIF1 MED31 N4BP3 NAB2 NR5A1 PCNA PPP1R16B PTEN RBM48 RFC2 RFC4 SUMO2 TASOR2 TRIM38 TSNAX UNC119 XAF1 XIAP YPEL3 ZMAT1 ZNF19 ZNF426	51 interacting genes: ARMC7 ATRIP BHLHB9 C1orf109 CARD9 CCDC33 CCDC85B CCNG2 CFAP206 COX5B CTNNA3 ERH FBF1 FXR1 GATA3 GPSM1 HGS HSF2BP KCTD9 KIFC3 KLHL40 LDOC1 LMO1 LONRF1 MDFI MEOX2 MID2 MKRN3 MLH1 MORN3 NEK6 PACRGL PIH1D2 PIK3R3 PNMA1 POLR1C PPP1R16B PRKAB2 PRKAR1B RFC5 SCAMP1 SERTAD3 SMARCB1 STAT3 TRIM23 TRIM42 TRIM73 TSEN15 USHBP1 YPEL3 ZNF76
Entrez ID		5985	54906
HPRD ID		02677	10695
Ensembl ID		ENSG00000111445	ENSG00000108021
Uniprot IDs		P40937 Q59GW7	Q5VWN6
PDB IDs		1LFS 6VVO
Enriched GO Terms of Interacting Partners?
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