BCHE and COLQ

Number of citations of the paper that reports this interaction (PubMedID 10529218)
13

Data Source:
HPRD (in vitro)

		BCHE	COLQ
Description		butyrylcholinesterase	collagen like tail subunit of asymmetric acetylcholinesterase
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nuclear Envelope Lumen Endoplasmic Reticulum Lumen Plasma Membrane Membrane Blood Microparticle	Collagen Trimer Basement Membrane Extracellular Space Plasma Membrane Cell Junction Extracellular Matrix Neuromuscular Junction Synaptic Cleft Collagen-containing Extracellular Matrix
	Molecular Function	Amyloid-beta Binding Catalytic Activity Acetylcholinesterase Activity Cholinesterase Activity Protein Binding Hydrolase Activity, Acting On Ester Bonds Enzyme Binding Choline Binding Identical Protein Binding Carboxylic Ester Hydrolase Activity	Extracellular Matrix Structural Constituent Protein Binding Heparin Binding
	Biological Process	Acetylcholine Catabolic Process Learning Negative Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Neuroblast Differentiation Choline Metabolic Process Response To Alkaloid Cocaine Metabolic Process Negative Regulation Of Synaptic Transmission Response To Glucocorticoid Response To Folic Acid	Acetylcholine Catabolic Process In Synaptic Cleft Regulation Of Synaptic Assembly At Neuromuscular Junction Extracellular Matrix Organization Skeletal Muscle Acetylcholine-gated Channel Clustering Establishment Of Protein Localization To Membrane
Pathways		Neurotransmitter clearance Synthesis of PC Synthesis, secretion, and deacylation of Ghrelin
Drugs		Choline Tacrine Dipivefrin Pyridostigmine Galantamine Isoflurophate Pralidoxime Malathion Donepezil Hexafluronium Demecarium Rivastigmine Edrophonium Echothiophate Ketamine Mivacurium Diethyl phosphonate Methylphosphinic Acid Butyric Acid 9-N-Phenylmethylamino-Tacrine 2-(N-morpholino)ethanesulfonic acid Ethyl dihydrogen phosphate Butyrylthiocholine Phenserine DODECANESULFONATE ION 9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE (1R)-menthyl hexyl phosphonate group (1S)-menthyl hexyl phosphonate group Ethyl hydrogen diethylamidophosphate Dichlorvos Choline salicylate
Diseases
GWAS		Alzheimer's disease biomarkers ( 23419831) Aspirin hydrolysis (plasma) ( 23508960) Blood protein levels ( 29875488) Butyrylcholinesterase levels ( 21862451) Cardiovascular disease risk factors ( 21943158) Fast beta electroencephalogram ( 28070124) FEV1 ( 30804560) Heart failure ( 20445134) Lung function (FEV1/FVC) ( 30804560) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Peak expiratory flow ( 30804560)	Diverticular disease ( 30177863 28585551) Diverticulitis ( 28585551)
Interacting Genes		4 interacting genes: COLQ SEC11A TRIM55 TRIM63	5 interacting genes: ACHE BCHE MRPS25 MUSK SGTB
Entrez ID		590	8292
HPRD ID		01519	04328
Ensembl ID		ENSG00000114200	ENSG00000206561
Uniprot IDs		P06276	Q9Y215
PDB IDs		1EHO 1EHQ 1KCJ 1P0I 1P0M 1P0P 1P0Q 1XLU 1XLV 1XLW 2J4C 2PM8 2WID 2WIF 2WIG 2WIJ 2WIK 2WIL 2WSL 2XMB 2XMC 2XMD 2XMG 2XQF 2XQG 2XQI 2XQJ 2XQK 2Y1K 3DJY 3DKK 3O9M 4AQD 4AXB 4B0O 4B0P 4BBZ 4BDS 4TPK 4XII 5DYT 5DYW 5DYY 5K5E 5LKR 5NN0 6EMI 6EP4 6EQP 6EQQ 6ESJ 6ESY 6EUL 6EYF 6EZ2 6F7Q 6I0B 6I0C 6I2T 6QAA 6QAB 6QAC 6QAD 6QAE 6R6V 6R6W 6RUA 6SAM 6T9P 6T9S 6XTA	1VZJ
Enriched GO Terms of Interacting Partners?
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