RALB and PLCD1

Number of citations of the paper that reports this interaction (PubMedID 15817490)
19

Data Source:
HPRD (two hybrid, in vitro)

		RALB	PLCD1
Description		RAS like proto-oncogene B	phospholipase C delta 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Midbody Extracellular Exosome	Cytoplasm Plasma Membrane Extracellular Exosome
	Molecular Function	GTPase Activity G Protein Activity Protein Binding GTP Binding GDP Binding Ubiquitin Protein Ligase Binding ATPase Binding	Phosphatidylinositol Phospholipase C Activity Calcium Ion Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding GTPase Activating Protein Binding
	Biological Process	Regulation Of Exocyst Assembly Positive Regulation Of Protein Phosphorylation Apoptotic Process Cell Cycle Signal Transduction Ras Protein Signal Transduction Cellular Response To Starvation Negative Regulation Of Protein Binding Positive Regulation Of Protein Binding Cell Division Regulation Of Exocyst Localization Cellular Response To Exogenous DsRNA Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Autophagosome Assembly	Phospholipid Metabolic Process Lipid Catabolic Process Phosphatidylinositol Metabolic Process Phosphatidylinositol-mediated Signaling
Pathways		p38MAPK events	Synthesis of IP3 and IP4 in the cytosol
Drugs			1D-myo-inositol 1,4,5-trisphosphate Inositol 2,4,5-trisphosphate
Diseases
GWAS		Breast size ( 27182965) Intraocular pressure ( 29617998) Mean platelet volume ( 32888494 27863252) Metabolite levels ( 23823483) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		8 interacting genes: CALM1 CXCR4 INCA1 PLCD1 RALBP1 REPS1 REPS2 RGL4	11 interacting genes: APP CALM1 GAP43 HGS KPNB1 NTAQ1 PAXIP1 RALA RALB TGM2 USP54
Entrez ID		5899	5333
HPRD ID		01550	09073
Ensembl ID		ENSG00000144118	ENSG00000187091
Uniprot IDs		A0A024RAG3 P11234	A0A384MR47 A8K8F9 P51178
PDB IDs		2KE5 2KWI 6ZQT 6ZRN
Enriched GO Terms of Interacting Partners?
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