RAD52 and KPNA3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RAD52	KPNA3
Description		RAD52 homolog, DNA repair protein	karyopherin subunit alpha 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Protein-containing Complex Protein-DNA Complex	Nucleus Nuclear Pore Nucleoplasm Cytosol Host Cell
	Molecular Function	DNA Binding Single-stranded DNA Binding Protein Binding Identical Protein Binding	Protein Binding Protein C-terminus Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Recombinase Assembly Double-strand Break Repair DNA Recombination Mitotic Recombination Cellular Response To DNA Damage Stimulus DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Cellular Response To Oxidative Stress Double-strand Break Repair Via Single-strand Annealing Regulation Of Nucleotide-excision Repair	NLS-bearing Protein Import Into Nucleus Viral Entry Into Host Cell Protein-containing Complex Assembly Viral Penetration Into Host Nucleus
Pathways		SUMOylation of DNA damage response and repair proteins HDR through Single Strand Annealing (SSA)	ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Body mass index ( 26426971) Eosinophil percentage of granulocytes ( 27863252) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Lung cancer ( 22899653) Neutrophil percentage of granulocytes ( 27863252) Small cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418) Youthful appearance (self-reported) ( 32339537)	Inflammatory skin disease ( 25574825) Menopause (age at onset) ( 22267201) Obesity-related traits ( 23251661) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Triiodothyronine/thyroxine ratio ( 30824882)
Interacting Genes		25 interacting genes: ABL1 AURKB DCP1A ERCC1 ERCC2 ERCC3 ERCC4 KPNA3 KPNA5 MCM2 MCM3 MEOX1 MEOX2 NFYC PAX5 PLK3 RAD51 RDM1 RPA1 RPA2 SEM1 SUMO1 TTK UBE2I WRN	54 interacting genes: ANKRD11 APOL6 ARNT BAHD1 BRD3 CCDC102B CDKN1B COIL CYHR1 DDX21 EPAS1 EPHA2 ERCC3 ESR2 FAM214B FAM50B FAM90A1 FTL GATA6 GRB10 GTF2H1 GTF2IRD1 HEXIM2 HIF1A HNRNPC HSPB1 KAT5 KPNB1 L3MBTL4 MAPK9 MAT2B MVP MYOD1 NFE2L2 NFKB1 NMNAT1 OGT POLR3C RAD52 RBBP4 RCC1 RPRD1A SLC5A11 TEX37 TGM2 TNIP3 TSSC4 UVSSA ZBTB24 ZCCHC10 ZCCHC12 ZNF131 ZNF76 ZNF764
Entrez ID		5893	3839
HPRD ID		11855	03536
Ensembl ID		ENSG00000002016	ENSG00000102753
Uniprot IDs		B7Z2G8 B7Z5Q6 F5GX32 P43351 Q5DR82	A0A024RDV7 O00505
PDB IDs		1H2I 1KN0 5JRB 5XRZ 5XS0
Enriched GO Terms of Interacting Partners?
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