BCAT2 and PTGDS

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		BCAT2	PTGDS
Description		branched chain amino acid transaminase 2	prostaglandin D2 synthase
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Nuclear Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Branched-chain-amino-acid Transaminase Activity L-leucine:2-oxoglutarate Aminotransferase Activity L-leucine Transaminase Activity L-valine Transaminase Activity L-isoleucine Transaminase Activity	Prostaglandin-D Synthase Activity Retinoid Binding Fatty Acid Binding Protein Binding Small Molecule Binding
	Biological Process	Isoleucine Catabolic Process Branched-chain Amino Acid Biosynthetic Process Leucine Biosynthetic Process Valine Biosynthetic Process Regulation Of Hormone Levels Cellular Response To Leukemia Inhibitory Factor	Prostaglandin Biosynthetic Process Cyclooxygenase Pathway Mast Cell Degranulation Regulation Of Circadian Sleep/wake Cycle, Sleep
Pathways		Branched-chain amino acid catabolism	Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Transcriptional regulation of testis differentiation
Drugs		Pyridoxal phosphate Glutamic acid Leucine Isoleucine Pyridoxamine-5'-Phosphate N-[O-Phosphono-Pyridoxyl]-Isoleucine alpha-Ketoisovalerate	Vitamin A
Diseases
GWAS		Long-term memory (delayed word recall task) ( 29970928) Resting metabolic rate ( 28476931) Serum metabolite levels ( 33031748)	Beta-trace protein levels ( 23328707) Blood protein levels ( 29875488) Corneal structure ( 23291589) Keratoconus ( 33649486)
Interacting Genes		4 interacting genes: ALDOA APP CREB3 PTGDS	22 interacting genes: ADRB2 AKT1 ARRB2 ATXN1 BCAT2 CACNA1A CAPN1 CARD10 CYSRT1 EGFR HK2 HK3 HSP90AA1 KRTAP10-3 KRTAP10-7 KRTAP12-3 MLH1 PTGER1 PTGER2 PTGFR SHBG UBQLN2
Entrez ID		587	5730
HPRD ID		00217	08904
Ensembl ID		ENSG00000105552	ENSG00000107317
Uniprot IDs		B3KSI3 O15382	A0A024R8G3 P41222
PDB IDs		1EKF 1EKP 1EKV 1KT8 1KTA 2A1H 2HDK 2HG8 2HGW 2HGX 2HHF 5BWR 5BWT 5BWU 5BWV 5BWW 5BWX 5CR5 5HNE 5I5S 5I5T 5I5U 5I5V 5I5W 5I5X 5I5Y 5I60 5MPR 6PRX	2WWP 3O19 3O22 3O2Y 4IMN 4IMO 4ORR 4ORS 4ORU 4ORW 4ORX 4ORY 4OS0 4OS3 4OS8 5WY9
Enriched GO Terms of Interacting Partners?
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