RAB5B and REEP5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		RAB5B	REEP5
Description		RAB5B, member RAS oncogene family	receptor accessory protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Plasma Membrane Endomembrane System Membrane Endocytic Vesicle Secretory Granule Membrane Early Endosome Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Exosome	Endoplasmic Reticulum Integral Component Of Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	GTPase Activity G Protein Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding	Molecular_function Protein Binding
	Biological Process	Intracellular Protein Transport Endocytosis Antigen Processing And Presentation Regulation Of Endocytosis Plasma Membrane To Endosome Transport	Endoplasmic Reticulum Organization Biological_process Regulation Of Intracellular Transport
Pathways		Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Olfactory Signaling Pathway
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Aspartate aminotransferase levels ( 33547301) Asthma ( 31959851 30929738 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) FEV1 ( 30804560) Gastroesophageal reflux disease ( 31527586) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 31928498) Lung function (FEV1) ( 30061609) Lung function (FEV1/FVC) ( 30804560) Medication use (drugs for peptic ulcer and gastro-oesophageal reflux disease) ( 31015401) Polycystic ovary syndrome ( 22885925 30566500) Refractive error ( 32231278) Sum eosinophil basophil counts ( 27863252) Type 1 diabetes ( 18198356) Vitiligo ( 22951725)	Attention deficit hyperactivity disorder ( 18839057) Daytime nap ( 33568662) Reaction time ( 29844566)
Interacting Genes		17 interacting genes: APOA5 CDK1 CHM EEA1 GLP1R PIK3CB PRIM1 RABAC1 REEP5 RIN1 RIN2 RIN3 SGSM3 SUN2 TBC1D15 TBC1D17 TFRC	22 interacting genes: ABHD4 ARFGAP1 ARFIP2 CD14 CHRM5 CPOX EDC3 GPX3 GTF2H1 HBEGF LGR5 NUDT3 PBX3 PDK4 PDLIM3 PITPNC1 RAB5B RABAC1 RGS2 SNX1 TENT4A VKORC1
Entrez ID		5869	7905
HPRD ID		01544	15918
Ensembl ID		ENSG00000111540	ENSG00000129625
Uniprot IDs		A0A024RB09 P61020	Q00765
PDB IDs		2HEI
Enriched GO Terms of Interacting Partners?
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