RAB1A and SYT5

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		RAB1A	SYT5
Description		RAB1A, member RAS oncogene family	synaptotagmin 5
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GO Annotations	Cellular Component	Golgi Membrane Early Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Endomembrane System Transport Vesicle Membrane Melanosome Extracellular Exosome	Plasma Membrane Axon Synaptic Vesicle Membrane Dense Core Granule Neuronal Cell Body Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Exocytic Vesicle Integral Component Of Neuronal Dense Core Vesicle Membrane Proximal Neuron Projection
	Molecular Function	GTPase Activity G Protein Activity Protein Binding GTP Binding Cadherin Binding	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Syntaxin Binding Clathrin Binding Protein Heterodimerization Activity
	Biological Process	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endocytosis Autophagy Golgi Organization Vesicle-mediated Transport Cell Migration Virion Assembly Growth Hormone Secretion Melanosome Transport Positive Regulation Of Interleukin-8 Production Substrate Adhesion-dependent Cell Spreading Defense Response To Bacterium Vesicle Transport Along Microtubule Cilium Assembly COPII-coated Vesicle Cargo Loading Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process	Chemical Synaptic Transmission Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Synaptic Vesicle Endocytosis Calcium Ion-regulated Exocytosis Of Neurotransmitter Cellular Response To Calcium Ion
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Regulation of insulin secretion
Drugs
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Triglyceride levels ( 32154731)	Platelet distribution width ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		31 interacting genes: ADCK1 CAPNS1 CDKN1A CHML CREB1 CSNK1D EBP FSCN1 GOLGA2 GOLGA5 GORASP2 HIVEP1 MAPRE3 MICAL1 MICALL1 OCRL PSMD7 RABAC1 RABEP1 RABGGTA RABGGTB RABIF RFK RUSC2 SLC16A8 SNRNP27 SNRPG SYT5 TBC1D17 USO1 ZNF593	8 interacting genes: DNAJC5 HTR6 MEGF8 NRXN1 POLR2E RAB1A SHANK3 SYT3
Entrez ID		5861	6861
HPRD ID		01538	02870
Ensembl ID		ENSG00000138069	ENSG00000129990
Uniprot IDs		B7Z8M7 P62820 Q5U0I6	A0A024R4N8 O00445 Q4FD32
PDB IDs		2FOL 2WWX 3L0I 3SFV 3TKL 4FMB 4FMC 4FMD 4FME 4IRU 4JVS	5H4Y 5H4Z
Enriched GO Terms of Interacting Partners?
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