PCYT2 and ADAMTS10

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		PCYT2	ADAMTS10
Description		phosphate cytidylyltransferase 2, ethanolamine	ADAM metallopeptidase with thrombospondin type 1 motif 10
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Endoplasmic Reticulum Membrane	Microfibril Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Ethanolamine-phosphate Cytidylyltransferase Activity Protein Binding	Molecular_function Metalloendopeptidase Activity Protein Binding Metal Ion Binding
	Biological Process	Phosphatidylethanolamine Biosynthetic Process Phospholipid Biosynthetic Process	Proteolysis Biological_process Extracellular Matrix Organization
Pathways		Synthesis of PE	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Appendicular lean mass ( 33097823) Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Atopic dermatitis ( 26482879) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body shape index ( 34021172) Body size at age 10 ( 32376654) Carpal tunnel syndrome ( 30833571) Height ( 28552196 20881960 25282103 18391951) Hip circumference adjusted for BMI ( 34021172) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Resting metabolic rate ( 28476931) Tonsillectomy ( 27182965 28928442) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 34021172 25673412) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		11 interacting genes: ADAMTS10 CLVS2 CRIP2 DNMT3B GDF9 HOXA1 INCA1 KDM8 PSMA1 REL SETDB1	7 interacting genes: ANXA7 CDKN1A HMGCL LAMTOR3 PCYT2 SMN1 TK1
Entrez ID		5833	81794
HPRD ID		04059	07470
Ensembl ID		ENSG00000185813	ENSG00000142303
Uniprot IDs		B3KSC8 B7Z4W6 I3L1R7 Q99447	A0A0A0MQW6 Q59FE5 Q6ZN14 Q9H324
PDB IDs		3ELB 4XSV
Enriched GO Terms of Interacting Partners?
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