ABCD3 and ACADM

		ABCD3	ACADM
Description		ATP binding cassette subfamily D member 3	acyl-CoA dehydrogenase medium chain
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Nucleus Mitochondrion Mitochondrial Matrix Axon Mitochondrial Membrane
	Molecular Function	Long-chain Fatty Acid Transporter Activity Protein Binding ATP Binding ATP Hydrolysis Activity ATPase-coupled Transmembrane Transporter Activity Protein Homodimerization Activity Protein Self-association Acyl-CoA Hydrolase Activity ABC-type Transporter Activity	Acyl-CoA Dehydrogenase Activity Identical Protein Binding Flavin Adenine Dinucleotide Binding Medium-chain-acyl-CoA Dehydrogenase Activity
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Peroxisome Organization Response To Xenobiotic Stimulus Response To Organic Cyclic Compound Bile Acid And Bile Salt Transport Long-chain Fatty Acid Import Into Peroxisome Very Long-chain Fatty Acid Catabolic Process Phytanic Acid Metabolic Process	Liver Development Glycogen Biosynthetic Process Regulation Of Gluconeogenesis Fatty Acid Beta-oxidation Response To Cold Post-embryonic Development Carnitine Metabolic Process, CoA-linked Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase Response To Starvation Carnitine Biosynthetic Process Medium-chain Fatty Acid Metabolic Process Medium-chain Fatty Acid Catabolic Process Cardiac Muscle Cell Differentiation
Pathways		ABC transporters in lipid homeostasis RHOA GTPase cycle RHOC GTPase cycle Class I peroxisomal membrane protein import	PPARA activates gene expression mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA
Drugs			Octanoyl-Coenzyme A Flavin adenine dinucleotide 3-thiaoctanoyl-CoA
Diseases
GWAS			Acylcarnitine levels ( 26068415) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Daytime sleep phenotypes ( 27126917) Glycine levels ( 31070104 30837465) Metabolic traits ( 21886157) Metabolite levels ( 20037589) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 33031748 23093944) Serum metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		7 interacting genes: ABCD1 ABCD2 ACADM COL6A2 PEX19 PSMA1 TUFT1	8 interacting genes: ABCD3 AGTR1 CALM1 CDC42 DBT DIRAS3 MSH4 SUMO4
Entrez ID		5825	34
HPRD ID		01368	08447
Ensembl ID		ENSG00000117528	ENSG00000117054
Uniprot IDs		P28288	A0A0S2Z366 B4DJE7 B7Z9I1 F6YB23 P11310 Q5HYG7 Q5T4U5
PDB IDs			1EGC 1EGD 1EGE 1T9G 2A1T 4P13
Enriched GO Terms of Interacting Partners?
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