PVR and PLA2G3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		PVR	PLA2G3
Description		PVR cell adhesion molecule	phospholipase A2 group III
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Plasma Membrane Adherens Junction Focal Adhesion Cell Surface Integral Component Of Membrane	Extracellular Region Extracellular Space Centriole Plasma Membrane Recycling Endosome
	Molecular Function	Virus Receptor Activity Protein Binding Signaling Receptor Activity Cell Adhesion Molecule Binding	Phospholipase A2 Activity Metal Ion Binding Calcium-dependent Phospholipase A2 Activity
	Biological Process	Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Viral Entry Into Host Cell Susceptibility To T Cell Mediated Cytotoxicity	Acrosome Assembly Production Of Molecular Mediator Involved In Inflammatory Response Phospholipid Metabolic Process Phosphatidylserine Metabolic Process Sperm Axoneme Assembly Negative Regulation Of Gene Expression Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Neuron Projection Development Lipoxygenase Pathway Positive Regulation Of Prostaglandin Biosynthetic Process Positive Regulation Of Prostaglandin Secretion Low-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Remodeling Macrophage Activation Mast Cell Degranulation Negative Regulation Of Neuron Apoptotic Process Phosphatidylethanolamine Metabolic Process Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process Phosphatidic Acid Metabolic Process Phosphatidylinositol Metabolic Process Cell Maturation Arachidonic Acid Secretion Cilium Assembly Positive Regulation Of Mast Cell Differentiation Positive Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Amyloid-beta Clearance Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Endocytic Recycling
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Nectin/Necl trans heterodimerization	Acyl chain remodelling of PC Acyl chain remodelling of PE Acyl chain remodelling of PG
Drugs		Sphingosine Myristic acid
Diseases
GWAS		Alzheimer's disease ( 24755620) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Mean platelet volume ( 32888494 27863252) Multiple sclerosis ( 21833088) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Platelet distribution width ( 32888494)	Fish- and plant-related diet ( 32066663) Gut microbiota (beta diversity) ( 27723756) Oily fish consumption ( 32066663) Paclitaxel-induced neuropathy ( 23776197) Pork consumption ( 32066663)
Interacting Genes		77 interacting genes: ADIPOQ ANKRD46 AP1M2 AQP10 BRICD5 C3orf52 CD226 CD47 CD96 CLDN19 CTXN3 CYB561A3 CYHR1 CYSRT1 DMPK DYNLT1 DYNLT3 EBP EDDM3B GMEB2 GPRC5D HHATL HOXA1 INSIG2 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-1 KRTAP3-3 KRTAP6-3 KRTAP9-3 MFSD11 NBPF19 NECTIN1 NECTIN2 NECTIN3 NINJ1 NINJ2 NOTCH2NLA OLFM4 PGA4 PLA2G3 PLAT PLP2 PLPP6 PSG11 PSG9 PSMD8 RUSF1 SCD SFTPC SLC22A4 SLC30A2 SLC35B4 SLC41A2 SMIM1 SNAP47 SYS1 TAS2R19 TIGIT TM6SF2 TMBIM6 TMEM147 TMEM229B TMEM54 TMEM65 TMEM79 TSPO VAMP5 VTN WNK1 ZDHHC15 ZDHHC22 ZFPL1	2 interacting genes: PVR TGFB1I1
Entrez ID		5817	50487
HPRD ID		01434	07144
Ensembl ID		ENSG00000073008	ENSG00000100078
Uniprot IDs		A0A0A0MSA9 A0A0C4DG49 A8K4I1 P15151	Q9NZ20
PDB IDs		1DGI 1NN8 3EPC 3EPD 3EPF 3J8F 3J9F 3UDW 3URO 4FQP 6ARQ 6ISC 6O3O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?