PTPRA and POFUT1

		PTPRA	POFUT1
Description		protein tyrosine phosphatase receptor type A	protein O-fucosyltransferase 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Receptor Complex Extracellular Exosome Schaffer Collateral - CA1 Synapse Integral Component Of Synaptic Membrane	Endoplasmic Reticulum Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding	Fucosyltransferase Activity Peptide-O-fucosyltransferase Activity
	Biological Process	Protein Phosphorylation Protein Dephosphorylation Integrin-mediated Signaling Pathway Insulin Receptor Signaling Pathway Peptidyl-tyrosine Dephosphorylation Modulation Of Chemical Synaptic Transmission Regulation Of Focal Adhesion Assembly	Angiogenesis Somitogenesis Fucose Metabolic Process Regulation Of Transcription, DNA-templated Protein O-linked Glycosylation Notch Signaling Pathway Nervous System Development Heart Development Regulation Of Notch Signaling Pathway O-glycan Processing Protein O-linked Fucosylation
Pathways		NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth RAF/MAP kinase cascade	Pre-NOTCH Processing in the Endoplasmic Reticulum
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 28552196) Immature fraction of reticulocytes ( 32888494) Monocyte count ( 32888494) Neutrophil count ( 32888494) White blood cell count ( 32888494)	Blood protein levels ( 30072576 29875488) Chronic obstructive pulmonary disease ( 28166215) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908)
Interacting Genes		18 interacting genes: BCAR1 CALM1 FYN GABARAPL2 GRB2 HSPB1 KCNA2 LINC00839 MBP POFUT1 PRKCD PTGER4 PTPRD PTPRF PTPRM PTPRS RET SRC	13 interacting genes: AKT2 DEFB115 DEFB116 DLL1 DUSP15 ERGIC3 ID1 JAG1 NAP1L2 NOTCH1 PTPRA USH2A ZIC3
Entrez ID		5786	23509
HPRD ID		01476	06319
Ensembl ID		ENSG00000132670	ENSG00000101346
Uniprot IDs		P18433	Q9H488
PDB IDs		6UZT	5UX6 5UXH
Enriched GO Terms of Interacting Partners?
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