CCAR2 and ZNF335

Number of citations of the paper that reports this interaction (PubMedID 19131338)
39

Data Source:
BioGRID (two hybrid)

		CCAR2	ZNF335
Description		cell cycle and apoptosis regulator 2	zinc finger protein 335
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Mitochondrial Matrix Spindle DBIRD Complex	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Complex Binding RNA Binding Enzyme Inhibitor Activity Protein Binding Enzyme Binding Nuclear Receptor Coactivator Activity	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated MRNA Processing Cellular Response To DNA Damage Stimulus Cell Cycle RNA Splicing Response To UV Wnt Signaling Pathway Negative Regulation Of Cell Growth Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA-templated Transcription, Elongation Regulation Of Circadian Rhythm Positive Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Rhythmic Process Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Deacetylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of DNA Damage Checkpoint	In Utero Embryonic Development Positive Regulation Of Neuroblast Proliferation Brain Development Regulation Of Gene Expression Cerebral Cortex Neuron Differentiation Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription By RNA Polymerase II Neuron Projection Morphogenesis Brain Morphogenesis Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Neurogenesis Regulation Of Histone H3-K4 Methylation Histone H3-K4 Trimethylation
Pathways		Regulation of HSF1-mediated heat shock response	Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Haemorrhoidal disease ( 33888516)	Abdominal aortic aneurysm ( 27899403) C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809) Celiac disease ( 25920553) Coronary artery disease ( 29212778 33020668) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Myocardial infarction ( 33532862)
Interacting Genes		13 interacting genes: AR BAG2 ELL FMR1 FXR1 FXR2 HTRA2 IKBKB MAILR MYC NLGN3 SUMO2 ZNF335	5 interacting genes: CCAR2 CDK4 CDK6 HSPB2 NCOA6
Entrez ID		57805	63925
HPRD ID		09159	11709
Ensembl ID		ENSG00000158941	ENSG00000198026
Uniprot IDs		Q8N163	Q8IW09 Q9H4Z2
PDB IDs
Enriched GO Terms of Interacting Partners?
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