GPAM and CIDEB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GPAM	CIDEB
Description		glycerol-3-phosphate acyltransferase, mitochondrial	cell death inducing DFFA like effector b
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Plasma Membrane Integral Component Of Membrane Mitochondrial Membrane	Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Glycerol-3-phosphate O-acyltransferase Activity Protein Binding Sn-1-glycerol-3-phosphate C16:0-DCA-CoA Acyl Transferase Activity	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Cytokine Production Glycerol-3-phosphate Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Diacylglycerol Biosynthetic Process Phosphatidic Acid Biosynthetic Process Phosphatidylglycerol Biosynthetic Process Phospholipid Biosynthetic Process Response To Glucose CDP-diacylglycerol Biosynthetic Process Triglyceride Biosynthetic Process Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Activated T Cell Proliferation Defense Response To Virus Fatty Acid Homeostasis Phospholipid Homeostasis Negative Regulation Of Activation-induced Cell Death Of T Cells	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Death Response To Nutrient Levels Bile Acid Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Execution Phase Of Apoptosis Activation Of Cysteine-type Endopeptidase Activity
Pathways		Synthesis of PA Activation of gene expression by SREBF (SREBP) Triglyceride biosynthesis RUNX1 regulates estrogen receptor mediated transcription Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 34315874 33339817) Alanine transaminase levels ( 29403010) Apolipoprotein A1 levels ( 32203549) Aspartate aminotransferase levels ( 33547301 34315874) Cholesterol, total ( 24097068 25961943 20686565) HDL cholesterol ( 30275531 25961943) HDL cholesterol levels ( 32203549 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Height ( 31562340) High density lipoprotein cholesterol levels ( 29403010 33339817) LDL cholesterol ( 24097068 30275531 25961943 20686565) LDL cholesterol levels ( 32203549 28334899 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Lean body mass ( 28552196) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731 33339817) Metabolite levels ( 31628463) Percent liver fat ( 34128465) Plateletcrit ( 32888494) Serum alkaline phosphatase levels ( 33547301 29403010 33339817) Total cholesterol levels ( 28334899 29403010 33339817 30275531) Triglyceride levels ( 32203549) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)	Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		3 interacting genes: APP CIDEB FBXO7	68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 C5orf38 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1
Entrez ID		57678	27141
HPRD ID		03865	11981
Ensembl ID		ENSG00000119927	ENSG00000136305
Uniprot IDs		Q86T70 Q8N1G6 Q9HCL2	Q9UHD4
PDB IDs			1D4B
Enriched GO Terms of Interacting Partners?
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