TSHZ3 and APEX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TSHZ3	APEX2
Description		teashirt zinc finger homeobox 3	apurinic/apyrimidinic endodeoxyribonuclease 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Plasma Membrane Growth Cone	Fibrillar Center Nucleus Nucleoplasm Mitochondrion Intracellular Membrane-bounded Organelle
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Metal Ion Binding	DNA Binding DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity Endonuclease Activity Protein Binding Phosphoric Diester Hydrolase Activity Zinc Ion Binding Double-stranded DNA 3'-5' Exodeoxyribonuclease Activity
	Biological Process	Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Synaptic Transmission, Glutamatergic Long-term Synaptic Potentiation	Base-excision Repair DNA Recombination Cell Cycle Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Chronotype ( 30696823) Cognitive performance ( 19734545) Corneal astigmatism ( 30306274) Diastolic blood pressure ( 27841878) Falling risk ( 32999390) FEV1 ( 30804560) Fractional exhaled nitric oxide (childhood) ( 24315451) General risk tolerance (MTAG) ( 30643258) Lung function (FEV1/FVC) ( 30061609 30804560) Peak expiratory flow ( 30804560) Photic sneeze reflex ( 27182965) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Post bronchodilator FEV1 in COPD ( 26634245) Refractive error ( 32231278) Systemising ( 31508503) Systolic blood pressure ( 27841878) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		31 interacting genes: ANKRA2 APBB1 APEX2 CCHCR1 CEP63 CEP70 COG6 CTBP1 CTBP2 GOLGA2 HSF2BP KASH5 KRT31 KRT40 LRRC73 MAD1L1 MRPL28 MTUS2 PIBF1 RINT1 ROPN1 SPAG5 TAX1BP1 TEPSIN TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TSC1 ZNF536	17 interacting genes: APP CALCOCO2 CCDC85B DAPK1 EFEMP2 HOOK2 LRRK2 MAP3K1 MFHAS1 MKRN3 NEDD4L NINL PCNA PGR TRAF2 TRIM37 TSHZ3
Entrez ID		57616	27301
HPRD ID		18351	06442
Ensembl ID		ENSG00000121297	ENSG00000169188
Uniprot IDs		Q63HK5	B4DWI9 B7ZA71 E5KN95 Q9UBZ4
PDB IDs		2DMI
Enriched GO Terms of Interacting Partners?
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