PITPNM2 and CPNE4

Number of citations of the paper that reports this interaction (PubMedID 12522145)
38

Data Source:
HPRD (in vitro, two hybrid)

		PITPNM2	CPNE4
Description		phosphatidylinositol transfer protein membrane associated 2	copine 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Endomembrane System Membrane Cell Body	Plasma Membrane Extracellular Exosome
	Molecular Function	Calcium Ion Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transfer Activity Receptor Tyrosine Kinase Binding Phosphatidylcholine Binding Phosphatidylinositol Binding	Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Phospholipid Transport Phosphatidylinositol-mediated Signaling Intermembrane Lipid Transfer	Cellular Response To Calcium Ion
Pathways		Synthesis of PI
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Asthma ( 32296059) Asthma (childhood onset) ( 30929738) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Educational attainment ( 25201988) Eosinophil percentage of white cells ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172 25673412) Hip index ( 34021172) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Macular thickness ( 30535121) Mean platelet volume ( 27863252) Menopause (age at onset) ( 26414677) Multiple sclerosis ( 31604244 24076602) Platelet count ( 21507922) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 28991256 25056061 29483656 23974872) Tourette syndrome ( 30818990) Type 2 diabetes ( 30054458) Uterine fibroids ( 31649266) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Adult body size ( 32376654) Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Amyotrophic lateral sclerosis ( 22959728) Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals ( 22959728) Body mass index ( 31453325 28892062 25673413) Body mass index variance ( 31453325) Body size at age 10 ( 32376654) Circulating leptin levels in high cardiovascular risk ( 31766143) Coronary artery aneurysm in Kawasaki disease ( 27171184) HDL cholesterol levels ( 32203549) Intracranial aneurysm ( 29531279) Iron status biomarkers (total iron binding capacity) ( 28334935) Metabolic syndrome ( 31589552) Motion sickness ( 25628336) Neutrophil count ( 21507922) Retinitis pigmentosa ( 33514863)
Interacting Genes		3 interacting genes: CPNE1 CPNE4 PTK2B	18 interacting genes: ACAD11 ACTB BCOR BICD1 CCDC22 CEP162 CPNE1 MAP2K1 MYCBP NECAB1 PDCD6 PITPNM2 PPP5C RDX SKIL SPTBN1 UBE2M UBE2O
Entrez ID		57605	131034
HPRD ID		08335	05017
Ensembl ID		ENSG00000090975	ENSG00000196353
Uniprot IDs		Q9BZ72 Q9UF51	B7Z370 Q4G168 Q96A23
PDB IDs
Enriched GO Terms of Interacting Partners?
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