NLGN2 and MDGA1

Number of citations of the paper that reports this interaction (PubMedID 23248271)
38

Data Source:
BioGRID (pull down)

		NLGN2	MDGA1
Description		neuroligin 2	MAM domain containing glycosylphosphatidylinositol anchor 1
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Presynaptic Membrane Cell Projection Synapse Postsynaptic Membrane Inhibitory Synapse Spanning Component Of Membrane Glycinergic Synapse Dopaminergic Synapse Symmetric, GABA-ergic, Inhibitory Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Postsynaptic Specialization Membrane	Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane Anchored Component Of Plasma Membrane GABA-ergic Synapse
	Molecular Function	Signaling Receptor Activity Neurexin Family Protein Binding Identical Protein Binding Cell Adhesion Molecule Binding	Molecular_function
	Biological Process	Regulation Of Respiratory Gaseous Exchange By Nervous System Process Neuron Cell-cell Adhesion Chemical Synaptic Transmission Synapse Assembly Sensory Perception Of Pain Positive Regulation Of Insulin Secretion Positive Regulation Of Synaptic Transmission, GABAergic Protein Localization To Synapse Locomotory Exploration Behavior Cell-cell Junction Maintenance Synaptic Vesicle Endocytosis Modulation Of Chemical Synaptic Transmission Synapse Organization Neuromuscular Process Controlling Balance Positive Regulation Of Synapse Assembly Positive Regulation Of Synaptic Transmission, Glutamatergic Terminal Button Organization Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Gephyrin Clustering Involved In Postsynaptic Density Assembly Postsynaptic Density Protein 95 Clustering Positive Regulation Of Inhibitory Postsynaptic Potential Cell-cell Adhesion Presynapse Assembly Positive Regulation Of Protein Localization To Synapse Inhibitory Synapse Assembly Regulation Of AMPA Receptor Activity Positive Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of Synaptic Vesicle Clustering	Neuron Migration Brain Development Spinal Cord Association Neuron Differentiation Cerebral Cortex Radially Oriented Cell Migration Regulation Of Synaptic Membrane Adhesion Regulation Of Presynapse Assembly
Pathways		Neurexins and neuroligins Neurexins and neuroligins	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Refractive error ( 32231278) Uterine fibroids ( 30194396) Waist circumference adjusted for body mass index ( 34021172)	Acne (severe) ( 24927181) Chronotype ( 30696823) Coronary artery aneurysm in Kawasaki disease ( 27171184) Daytime nap ( 33568662) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Lamb consumption ( 32066663) Neurological blood protein biomarker levels ( 31320639) Restless legs syndrome ( 29029846)
Interacting Genes		9 interacting genes: DLG2 DLG3 DLG4 DNAH9 MDGA1 NRXN1 NRXN2 NRXN3 PATJ	2 interacting genes: LNX2 NLGN2
Entrez ID		57555	266727
HPRD ID		07348	14374
Ensembl ID		ENSG00000169992	ENSG00000112139
Uniprot IDs		Q8NFZ4	Q8NFP4
PDB IDs		5XEQ	5V5V 5V5W 5XEQ
Enriched GO Terms of Interacting Partners?
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