KLHL42 and STXBP4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		KLHL42	STXBP4
Description		kelch like family member 42	syntaxin binding protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Cytosol Cul3-RING Ubiquitin Ligase Complex	Cytoplasmic Vesicle Phagocytic Vesicle Extracellular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding	Protein Binding Syntaxin Binding
	Biological Process	Protein Polyubiquitination Cell Cycle Regulation Of Microtubule-based Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cell Division	Protein Targeting Cellular Response To DNA Damage Stimulus Insulin Receptor Signaling Pathway Regulation Of Glucose Transmembrane Transport Positive Regulation Of Keratinocyte Proliferation Protein Stabilization Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cellular Response To Interferon-gamma Positive Regulation Of Cell Cycle G1/S Phase Transition
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Gut microbiota (functional units) ( 27694959) Height ( 31562340) Osteoarthritis (hip) ( 30664745) Refractive error ( 32231278) Resting heart rate ( 27798624) Type 2 diabetes ( 30054458)	Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Intrinsic epigenetic age acceleration ( 29374233) Menarche (age at onset) ( 25231870) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494) Systolic blood pressure ( 34074324) Zinc levels ( 26025379)
Interacting Genes		35 interacting genes: ADD1 ANKRD33 CALCOCO2 CDCA4 CKMT2 COIL CT55 CUL3 DAZAP2 DDI1 FAM168A INCA1 KRTAP19-4 MYOG OIP5 OSTF1 P4HB PFDN5 POMC RCN3 REL SERTAD1 SERTAD3 SSX2IP STAM2 STXBP4 TRIM23 TRIM54 TTC23 UBE2E3 UBQLN1 UBQLN2 UBQLN4 USHBP1 VPS52	6 interacting genes: ATN1 DYNLL2 ENKD1 KLHL42 STX4 TRIM54
Entrez ID		57542	252983
HPRD ID		17237	18127
Ensembl ID		ENSG00000087448	ENSG00000166263
Uniprot IDs		B2RNT7 F5H523 Q9P2K6	B5MCT9 Q6ZWJ1
PDB IDs			2YSG
Enriched GO Terms of Interacting Partners?
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