ZNF398 and CHD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZNF398	CHD2
Description		zinc finger protein 398	chromodomain helicase DNA binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA Helicase Activity RNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Histone Binding ATP-dependent Chromatin Remodeler Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Muscle Organ Development DNA Duplex Unwinding Hematopoietic Stem Cell Differentiation
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494) Sum eosinophil basophil counts ( 27863252)	Adolescent idiopathic scoliosis ( 30395268) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Daytime nap ( 33568662) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Pulse pressure ( 30224653)
Interacting Genes		23 interacting genes: - AQP1 C1orf109 CABP5 CHD2 CHPF2 CIB3 CLK2 DGCR6 ELMO1 EMD ESR1 GPATCH2L MAGOHB MFAP1 NCDN NDE1 NUDT22 OPTN PLEKHF2 SMARCB1 TRIM41 ZNF783	12 interacting genes: BEND7 ELOA2 MEOX2 MID2 NR2F2 SRPK2 TEKT1 THAP1 TRIM41 TRIM54 TULP3 ZNF398
Entrez ID		57541	1106
HPRD ID		18336	03669
Ensembl ID		ENSG00000197024	ENSG00000173575
Uniprot IDs		A0A090N7S8 A0A090N8F2 B4DXA9 Q8TD17	O14647
PDB IDs
Enriched GO Terms of Interacting Partners?
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