GATAD2B and SBK3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GATAD2B	SBK3
Description		GATA zinc finger domain containing 2B	SH3 domain binding kinase family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm NuRD Complex Nuclear Speck Protein-containing Complex
	Molecular Function	Protein Binding Zinc Ion Binding Nucleosomal DNA Binding Sequence-specific DNA Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling	Protein Phosphorylation
Pathways		HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Potential therapeutics for SARS
Drugs			Fostamatinib
Diseases
GWAS		Age at first birth ( 27798627) Age at first sexual intercourse ( 34211149) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Empathy quotient ( 29527006) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) General cognitive ability ( 29844566) Height ( 31562340) Lentiform nucleus volume ( 22903471) Number of children ever born ( 27798627) Raw vegetable consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		29 interacting genes: CALCOCO2 CDKN2D CEP70 ERCC6 FHL2 GOLGA2 GPSM3 H2AC20 H2BC21 H3C1 H4C1 KAT2B MBD2 MBD3 MTNR1A NGB NME7 NOXA1 PRKAB2 RBPMS RPGRIP1 SBK3 SMAD2 SUMO2 TEX11 TRAF1 TRIM27 USHBP1 ZGPAT	13 interacting genes: AIMP2 ATXN7L2 C1orf105 CRY2 DMAP1 EXOSC2 GATAD2B MBD3L2 NOTO POLDIP3 SMAD3 SNRNP35 TNNT1
Entrez ID		57459	100130827
HPRD ID		15094
Ensembl ID		ENSG00000143614	ENSG00000231274
Uniprot IDs		Q8WXI9	P0C264
PDB IDs
Enriched GO Terms of Interacting Partners?
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