BIRC6 and EXOC3

Number of citations of the paper that reports this interaction (PubMedID 18329369)
83

Data Source:
HPRD (in vivo)

		BIRC6	EXOC3
Description		baculoviral IAP repeat containing 6	exocyst complex component 3
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Endosome Trans-Golgi Network Microtubule Organizing Center Membrane Midbody Flemming Body	Exocyst Golgi Apparatus Cytosol Growth Cone Midbody Secretory Granule Membrane Presynaptic Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Ubiquitin Conjugating Enzyme Activity	SNARE Binding Protein Binding Cadherin Binding
	Biological Process	Protein Phosphorylation Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Cell Cycle Positive Regulation Of Cell Population Proliferation Negative Regulation Of Endopeptidase Activity Protein Ubiquitination Regulation Of Cytokinesis Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Cell Division Labyrinthine Layer Development Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Exocytosis Protein Transport Exocyst Localization
Pathways		ALK mutants bind TKIs Signaling by ALK fusions and activated point mutants	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Chronotype ( 30696823) Coffee consumption ( 31046077) General risk tolerance (MTAG) ( 30643258) Male-pattern baldness ( 28196072) Red cell distribution width ( 32888494) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Hypospadias ( 25108383) Red blood cell count ( 32888494) Ulcerative colitis ( 21297633)
Interacting Genes		23 interacting genes: ALK BIRC5 CASP3 CASP7 CASP8 CASP9 CDK1 CSNK2A1 DIABLO EXOC3 EXOC4 GABARAP HTRA2 MAP1LC3B MAP2K1 PLK1 RAB8A RACK1 RNF41 UBE2D1 USP8 VAV2 VCL	12 interacting genes: APP BIRC6 BUB3 EXOC2 FSD2 GMCL1 MAILR MLH1 PPP1R12C RALA TERT VAMP2
Entrez ID		57448	11336
HPRD ID		05731	09738
Ensembl ID		ENSG00000115760	ENSG00000180104
Uniprot IDs		Q9NR09	A0A024QYZ6 O60645 Q69YP2
PDB IDs		3CEG
Enriched GO Terms of Interacting Partners?
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