MIR451A and PGAM5

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		MIR451A	PGAM5
Description		microRNA 451a	PGAM family member 5, mitochondrial serine/threonine protein phosphatase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Exosome Extracellular Vesicle	Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	Protein Serine/threonine Phosphatase Activity GTPase Activator Activity Protein Binding Phosphatase Activity Protein-containing Complex Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Negative Regulation Of Transporter Activity Gene Silencing By MiRNA Positive Regulation Of Vascular Wound Healing Positive Regulation Of Apoptotic Process Negative Regulation Of Protein Kinase B Signaling Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Macroautophagy Peptidyl-threonine Dephosphorylation Regulation Of Catalytic Activity Necroptotic Process Positive Regulation Of Mitochondrial Fission Negative Regulation Of Cold-induced Thermogenesis
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin concentration ( 29403010)	Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		76 interacting genes: AIMP1 AIMP2 APOBEC3B AQR C1QBP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 FUS GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUDT21 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SUGP2 SYNCRIP TAF15 TENT2 TRA2A TRA2B UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346	30 interacting genes: HSPA1B MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR141 MIR145 MIR15A MIR16-1 MIR18B MIR200B MIR205 MIR206 MIR20B MIR21 MIR214 MIR25 MIR34A MIR451A MIR93 MIRLET7A1 MIRLET7A2 MIRLET7B MIRLET7E MIRLET7F1 SETDB1 UBE4B YWHAG ZBTB16
Entrez ID		574411	192111
HPRD ID			14681
Ensembl ID		ENSG00000284565	ENSG00000247077
Uniprot IDs			Q96HS1
PDB IDs			3MXO 3O0T 5MUF 6CNI 6CNL
Enriched GO Terms of Interacting Partners?
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