RAB22A and ALS2CL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		RAB22A	ALS2CL
Description		RAB22A, member RAS oncogene family	ALS2 C-terminal like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Early Endosome Late Endosome Plasma Membrane Endosome Membrane Endomembrane System Actin Cytoskeleton Phagocytic Vesicle Membrane Phagocytic Vesicle Extracellular Exosome	Cytosol
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	GTPase Activator Activity Protein Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Endocytosis Endosome Organization Regulation Of Vesicle Size	Endosome Organization Regulation Of Catalytic Activity
Pathways		RAB geranylgeranylation	RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429) Childhood asthma exacerbations in long-acting beta2-agonist treatment ( 33706416) Metabolite levels ( 23823483) Nickel levels ( 26025379)
Interacting Genes		7 interacting genes: ALS2CL APPL2 EEA1 RAB3GAP1 RAB7A RABAC1 SMURF2	7 interacting genes: EEF1AKMT3 PPP1R32 RAB22A RAB31 RAB5A RAB5C RSPH14
Entrez ID		57403	259173
HPRD ID		06696	10643
Ensembl ID		ENSG00000124209	ENSG00000178038
Uniprot IDs		Q9UL26	A0A024R2U1 Q60I27
PDB IDs
Enriched GO Terms of Interacting Partners?
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