VANGL2 and ARFRP1

Number of citations of the paper that reports this interaction (PubMedID 23326640)
38

Data Source:
BioGRID (pull down)

		VANGL2	ARFRP1
Description		VANGL planar cell polarity protein 2	ADP ribosylation factor related protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Integral Component Of Membrane Apical Plasma Membrane Lateral Plasma Membrane	Golgi Apparatus Trans-Golgi Network Cytosol Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Establishment Of Planar Polarity Neural Tube Closure Heart Looping Cell Migration Involved In Kidney Development Apical Protein Localization Wnt Signaling Pathway, Planar Cell Polarity Pathway Non-motile Cilium Assembly	Intracellular Protein Transport Signal Transduction Gastrulation Protein Localization To Organelle Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport
Pathways		PCP/CE pathway Asymmetric localization of PCP proteins RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle	Retrograde transport at the Trans-Golgi-Network Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive performance ( 19734545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Left-handedness ( 32989287) Multiple sclerosis ( 31604244 24076602) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systemic lupus erythematosus ( 28714469)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 30604766) Inflammatory bowel disease ( 28067908) Platelet count ( 32888494) Prostate cancer ( 23535732) Refractive error ( 32231278) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408) Ulcerative colitis ( 28067908)
Interacting Genes		5 interacting genes: AP1M1 ARFRP1 DVL1 MAGI3 SQSTM1	7 interacting genes: AP1G1 AP1M1 CYTH1 DNAJB13 GLP1R SMAD4 VANGL2
Entrez ID		57216	10139
HPRD ID		02758	05264
Ensembl ID		ENSG00000162738	ENSG00000101246
Uniprot IDs		A8K4L6 Q9ULK5	A0A384P5U7 B7ZKY8 Q13795
PDB IDs
Enriched GO Terms of Interacting Partners?
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