THAP11 and NUTF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		THAP11	NUTF2
Description		THAP domain containing 11	nuclear transport factor 2
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GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytosol	Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytosol Nuclear Membrane Nuclear Pore Central Transport Channel Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding	Protein Binding Structural Constituent Of Nuclear Pore Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Protein Import Into Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Positive Regulation Of Protein Import Into Nucleus MRNA Transport Protein Localization To Nuclear Pore Negative Regulation Of Vascular Endothelial Growth Factor Production
Pathways
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 27863252) Schizophrenia ( 25056061 29483656)	Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		21 interacting genes: BBLN CASP3 CTBP1 ECT2 HCFC1 HDAC1 HDAC3 HEMGN L3MBTL2 LRRC45 MCPH1 NUTF2 OGT PFDN6 PSMC5 SIN3A SLX1B SRSF11 THAP7 TPX2 VPS52	55 interacting genes: BEND7 BRWD1 CAMK2G CANX CCDC106 CCDC150 CCDC158 CHCHD3 CHMP4A CKMT1A CKMT1B CLPP FAM50B GLRX2 HMG20A HMG20B KHDC4 KPNB1 KRT86 KRTAP9-8 LASP1 LCE1C LCE5A LENG1 LUC7L2 MRNIP MYOZ3 NFAT5 NME1 NME4 NRIP3 NUP153 NUP54 NUP62 PAX4 PBX4 PCNA PFKP PHF11 PPP1R16A PTMA RAN RPRD1B SF3B3 SPATC1L SPRY4 TERF2 TEX35 THAP11 THAP3 TLE5 UBAP2 WWP2 YAF2 ZMAT2
Entrez ID		57215	10204
HPRD ID		11629	12050
Ensembl ID		ENSG00000168286	ENSG00000102898
Uniprot IDs		Q96EK4	A0A024R6Y2 P61970
PDB IDs		2LAU 5AJS	1GY5
Enriched GO Terms of Interacting Partners?
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