DENND11 and SETBP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		DENND11	SETBP1
Description		DENN domain containing 11	SET binding protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleoplasm Cytosol Nuclear Body
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity	DNA Binding Protein Binding
	Biological Process	Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS			Adult body size ( 32376654) Bone ultrasound measurement (velocity of sound) ( 28472463) Breast cancer ( 25751625 29059683 31757997) Coronary artery aneurysm in Kawasaki disease ( 27171184) Diastolic blood pressure ( 27618452) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Estimated glomerular filtration rate ( 31152163) Hair color ( 26926045) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Male-pattern baldness ( 29146897 22693459 28196072) Mean platelet volume ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Neonatal white matter microstructure ( 33009551) Number of sexual partners ( 30643258) Platelet thrombus formation ( 22550155) Pulse pressure ( 27841878) QRS duration ( 30679814 27577874 30012220 25035420 27659466) QRS interval (sulfonylurea treatment interaction) ( 27958378) Refractive error ( 32231278) Restless legs syndrome ( 29029846) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 27841878 28739976 27618452) Waist circumference ( 28552196) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
Interacting Genes		1 interacting genes: SETBP1	14 interacting genes: APP DENND11 LRRC37A11P PLEKHF2 SET SPANXA1 SPANXA2 SPANXC SPANXD SUMO1P1 TCF4 UBE2I XAGE1B YAF2
Entrez ID		57189	26040
HPRD ID		13976	10224
Ensembl ID		ENSG00000257093	ENSG00000152217
Uniprot IDs		A4D1U4	Q9Y6X0
PDB IDs
Enriched GO Terms of Interacting Partners?
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