AGTRAP and GDNF

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		AGTRAP	GDNF
Description		angiotensin II receptor associated protein	glial cell derived neurotrophic factor
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle	Extracellular Region Extracellular Space Golgi Apparatus
	Molecular Function	Angiotensin Type II Receptor Activity Protein Binding	Signaling Receptor Binding Protein Binding Growth Factor Activity Glial Cell-derived Neurotrophic Factor Receptor Binding Receptor Tyrosine Kinase Binding Protein Homodimerization Activity Chemoattractant Activity Involved In Axon Guidance
	Biological Process	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway	Metanephros Development Branching Involved In Ureteric Bud Morphogenesis Neural Crest Cell Migration Organ Induction Postsynaptic Membrane Organization Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Signal Transduction Nervous System Development Peripheral Nervous System Development Positive Regulation Of Cell Population Proliferation Adult Locomotory Behavior Regulation Of Gene Expression Dorsal Spinal Cord Development Postganglionic Parasympathetic Fiber Development Peristalsis Neuron Projection Development Positive Regulation Of Monooxygenase Activity Positive Regulation Of Dopamine Secretion Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II MRNA Stabilization Enteric Nervous System Development Sympathetic Nervous System Development Embryonic Organ Development Regulation Of Dopamine Uptake Involved In Synaptic Transmission Ureteric Bud Formation Regulation Of Morphogenesis Of A Branching Structure Chemoattraction Of Axon Commissural Neuron Axon Guidance Positive Regulation Of Ureteric Bud Formation Positive Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Regulation Of Stem Cell Differentiation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Semaphorin-plexin Signaling Pathway
Pathways		Signaling by BRAF and RAF1 fusions	NCAM1 interactions RAF/MAP kinase cascade RET signaling
Drugs			Chondroitin sulfate
Diseases
GWAS		Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Basophil percentage of white cells ( 32888494) Systolic blood pressure ( 19430483)	Asthma ( 29273806) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Major depressive disorder ( 20125088)
Interacting Genes		138 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 ANKS6 AP3M1 APOA4 AQP6 ARAF ARFIP2 ARHGAP1 ATP5F1E BCL2L13 BPIFA2 CAPNS1 CCDC70 CD160 CD79A CELA3A CIAO2A COQ8A CPLX1 CPLX4 CRCT1 CYB5R3 CYBC1 DDA1 DDX55 DGCR6 DIABLO DNAJC1 ECPAS ERGIC3 ETFRF1 FAM114A1 FAM209A FARS2 FASTKD3 FATE1 FFAR2 FGA FHIP1B FNDC9 GABARAPL2 GAD1 GAD2 GDNF GPR152 GPX8 GTF2H1 GTF3C1 H4C7 HARS2 HIBADH HMGB1 HSBP1L1 HSCB HSD17B13 HSFX1 HSFX2 HSPA4 IL7R ISCU KCNK5 KIR2DL3 KIR3DL3 LMNA LMO2 LNX1 LRRC4C LRRC59 MCEE MGST3 MIEF1 MIEF2 MMD MRM1 MRPL11 MRRF MTERF3 MUTYH MYG1 NDRG4 NDUFAF3 NFU1 NFYB NKG7 PBX3 PCTP PCYT1A PDHX PIMREG PITPNC1 PNPO POLDIP2 PPIF PRPF18 PTPN9 RAB30 RACK1 RBFA RETREG3 RMDN2 S100B SCAND1 SENP2 SH3GLB1 SLC18A1 SLC7A14 SMG9 SNX1 SPG21 SSX3 SSX5 STAG3L1 STAR STARD4 STMN4 STX1A SUCLA2 SYT16 TBRG4 TCEA2 TCEANC2 TFAM THAP4 TMEM139 TMEM14B TMEM31 TMPPE TPD52L3 TTPA TUBA1B TXN2 UBE2I YARS2 ZFYVE21 ZNF391	8 interacting genes: AGTRAP GFRA1 GFRA2 MUC1 NCAM1 RET SCAMP5 SYP
Entrez ID		57085	2668
HPRD ID		16379	02906
Ensembl ID		ENSG00000177674	ENSG00000168621
Uniprot IDs		Q6RW13	A0A0S2Z3T2 A0A0S2Z3V2 P39905
PDB IDs			2V5E 3FUB 4UX8 6Q2N
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?