RGMA and PPP1R16A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RGMA	PPP1R16A
Description		repulsive guidance molecule BMP co-receptor a	protein phosphatase 1 regulatory subunit 16A
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Cell Surface Anchored Component Of Membrane Neuron Projection	Plasma Membrane
	Molecular Function	Protein Binding Coreceptor Activity Transferrin Receptor Binding	Protein Binding Protein Phosphatase 1 Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity
	Biological Process	Neural Tube Closure Positive Regulation Of Neuron Projection Development BMP Signaling Pathway Regulation Of BMP Signaling Pathway Neuron Projection Development Positive Regulation Of GTPase Activity Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Positive Regulation Of Membrane Protein Ectodomain Proteolysis Negative Regulation Of Receptor Binding	Regulation Of Protein Dephosphorylation Regulation Of Catalytic Activity
Pathways		Netrin-1 signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Copper levels ( 26025379) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Opioid dependence ( 29478698) Overweight status ( 25133637) Periodontitis (CDC/AAP) ( 24024966) Refractive error ( 32231278) Response to angiotensin II receptor blocker therapy (opposite direction w/ diuretic therapy) ( 22566498) Type 1 diabetes nephropathy ( 23028342) Type 2 diabetes ( 32499647)	Age at first birth ( 27798627) Blood metabolite levels ( 26401656) Educational attainment ( 25201988) Height ( 28552196) Mean corpuscular hemoglobin concentration ( 32888494 27863252)
Interacting Genes		5 interacting genes: CRTC3 PPP1R16A SGSM2 TERF2IP TP53BP2	52 interacting genes: ANTKMT ATP23 ATXN7L2 AVPI1 BATF2 C1orf216 C3orf36 CCDC116 CDCA7L CDH24 CKMT1A CKMT1B DDX27 FSD1 HDAC7 HGS HLA-E IDO1 IL16 KAT5 KRTAP19-5 LY6H LZTS2 MCCD1 MRPL12 MYOM1 NDUFAB1 NEK6 NUTF2 PAPSS1 PBDC1 PHPT1 PPP1CA PPP1CB PPP1CC PRKAB2 PRPF31 PUF60 RFLNB RGMA SCNM1 SUV39H1 TFIP11 TLE5 TPP2 TRIP6 TSSK3 TTC23 TXNRD1 UNKL ZFYVE26 ZNF414
Entrez ID		56963	84988
HPRD ID		09560	16454
Ensembl ID		ENSG00000182175	ENSG00000160972
Uniprot IDs		A0A0A0MTQ4 Q96B86	Q96I34
PDB IDs		4UHY 6Z3G
Enriched GO Terms of Interacting Partners?
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