PRTFDC1 and RAB18

		PRTFDC1	RAB18
Description		phosphoribosyl transferase domain containing 1	RAB18, member RAS oncogene family
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GO Annotations	Cellular Component		Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Plasma Membrane Endomembrane System Apical Plasma Membrane Secretory Granule Membrane Synapse Endoplasmic Reticulum Tubular Network
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Protein Homodimerization Activity	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Purine Ribonucleoside Salvage Guanine Salvage GMP Catabolic Process	Eye Development Intracellular Protein Transport Small GTPase Mediated Signal Transduction Brain Development Lipid Droplet Organization Endoplasmic Reticulum Tubular Network Organization
Pathways			Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Body shape index ( 34021172) Diisocyanate-induced asthma ( 25918132) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Intraocular pressure ( 29617998) Lymphocyte counts ( 32888494 27863252) Metabolite levels (Pyroglutamine) ( 23934736) Monocyte count ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Obesity-related traits ( 23251661) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494 27863252) Post-traumatic stress disorder ( 25456346) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)	Benign childhood epilepsy with centro-temporal spikes ( 32580138) Body shape index ( 34021172) Childhood ear infection ( 27182965 28928442) Diisocyanate-induced asthma ( 25918132) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Hip circumference adjusted for BMI ( 28552196) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		21 interacting genes: - CNRIP1 DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 GPR158 HPRT1 LGALS9B LNX1 MCMBP NIF3L1 NTAQ1 RAB18 SPG21 STAT5A TCL1A TMEM14B VWA5A	15 interacting genes: APBB1IP AQP6 CHM DVL3 ELOVL4 ERRFI1 FAM107A PDE6D PPP2R1A PPP2R1B PRTFDC1 TAX1BP1 TOM1L1 TREH UCN
Entrez ID		56952	22931
HPRD ID		17917	03731
Ensembl ID		ENSG00000099256	ENSG00000099246
Uniprot IDs		Q9NRG1	A0A087X163 B7Z4P9 B7Z5V3 Q9NP72
PDB IDs		2JBH	1X3S
Enriched GO Terms of Interacting Partners?
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