XAB2 and ERCC8

Number of citations of the paper that reports this interaction (PubMedID 10944529)
46

Data Source:
HPRD (in vivo, in vitro)

		XAB2	ERCC8
Description		XPA binding protein 2	ERCC excision repair 8, CSA ubiquitin ligase complex subunit
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GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Membrane Intracellular Membrane-bounded Organelle U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex	Nucleotide-excision Repair Complex Nucleus Nucleoplasm Nuclear Matrix Cul4A-RING E3 Ubiquitin Ligase Complex Protein-containing Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Protein-containing Complex Binding
	Biological Process	Generation Of Catalytic Spliceosome For First Transesterification Step MRNA Splicing, Via Spliceosome Blastocyst Development Transcription-coupled Nucleotide-excision Repair Transcription, DNA-templated Cerebral Cortex Development	Single Strand Break Repair Protein Polyubiquitination Transcription-coupled Nucleotide-excision Repair Cellular Response To DNA Damage Stimulus Response To Oxidative Stress Response To UV Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Regulation Of Transcription-coupled Nucleotide-excision Repair Double-strand Break Repair Via Classical Nonhomologous End Joining
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway	Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Neddylation
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		17 interacting genes: CACHD1 DHX16 ERCC6 ERCC8 GLIS2 ILF3 ISY1 MIR106B MIR34B MIRLET7E MIRLET7G MIRLET7I POLR2A PPIE SMAD9 SUMO2 XPA	12 interacting genes: ADAMTS6 CAMK2D CBR1 CSNK2B CUL4B DDB1 ERCC6 GTF2H2 RBX1 TOP1 UQCRQ XAB2
Entrez ID		56949	1161
HPRD ID		18306	07523
Ensembl ID		ENSG00000076924	ENSG00000049167
Uniprot IDs		Q9HCS7	A0A0S2Z3L1 B3KPW7 B4DGZ9 Q13216
PDB IDs		5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P 7ABI	4A11 6FCV
Enriched GO Terms of Interacting Partners?
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