EMSY and CBX1

Number of citations of the paper that reports this interaction (PubMedID 14651845)
129

Data Source:
HPRD (in vitro, in vivo)

		EMSY	CBX1
Description		EMSY transcriptional repressor, BRCA2 interacting	chromobox 1
Image
GO Annotations	Cellular Component	Nucleoplasm	Chromosome, Centromeric Region Chromosome, Telomeric Region Chromatin Heterochromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Pericentric Heterochromatin Spindle Chromocenter Site Of DNA Damage
	Molecular Function	Protein Binding Identical Protein Binding	Chromatin Binding Protein Binding Enzyme Binding Identical Protein Binding Histone Methyltransferase Binding
	Biological Process	DNA Repair Chromatin Organization Regulation Of Transcription, DNA-templated	Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated
Pathways			HCMV Early Events
Drugs
Diseases
GWAS		Allergic rhinitis ( 31361310) Asthma ( 31361310 31959851 34103634 29273806) Asthma (adult onset) ( 31036433) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Eczema ( 31361310) Eosinophil counts ( 29403010) Type 1 diabetes ( 34012112)	Aspartate aminotransferase levels ( 33547301) Body mass index ( 26426971 20935630) Caffeine consumption from coffee ( 33287642) Caffeine consumption from coffee or tea ( 33287642) Generalized epilepsy ( 22949513)
Interacting Genes		14 interacting genes: AIDA AKT1 BRCA2 CBX1 CLVS2 DDIT3 DISC1 GET3 H3-4 LIX1 PSMA1 ZMYND11 ZNF131 ZNF646	37 interacting genes: ABI3BP ARL5A ATXN7L2 BAHD1 BARD1 BRCA1 CBX3 CBX5 CHAF1A DCAF7 DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LNX1 LRIF1 NR2F6 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TBKBP1 TRIM24 TRIM28 UCHL1 VHL VTN ZNF280C
Entrez ID		56946	10951
HPRD ID		10544	05149
Ensembl ID		ENSG00000158636	ENSG00000108468
Uniprot IDs		Q7Z589	P83916 Q6IBN6
PDB IDs		1UTU 1UZ3 2FMM	2FMM 3F2U 3Q6S 5T1G 6D07 6D08
Enriched GO Terms of Interacting Partners?
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