TRIM39 and PLCD4

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
HPRD (two hybrid)

		TRIM39	PLCD4
Description		tripartite motif containing 39	phospholipase C delta 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Phosphatidylinositol Phospholipase C Activity Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding
	Biological Process	Apoptotic Process Mitotic G2 DNA Damage Checkpoint Signaling Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Protein Stabilization Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway	Acrosome Reaction Lipid Catabolic Process Phosphatidylinositol Metabolic Process Phosphatidylinositol-mediated Signaling Regulation Of Catalytic Activity
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS		Anxiety ( 33859377) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cutaneous lupus erythematosus ( 25827949) Neuroticism ( 29255261)	Blood urea nitrogen levels ( 31152163) Height ( 25429064) Male-pattern baldness ( 28196072)
Interacting Genes		62 interacting genes: APP BTNL2 CACTIN CCNC DCUN1D1 DCX DIP2A EIF4A2 EPHB6 GAMT HINFP KDM1A LMNA LNX1 LXN MED18 MNAT1 MTURN OTUB2 OTUD6A PDLIM5 PLCD4 POLI PRPF3 PSMA6 PSMB1 PSMD9 RAD23A RECK RNF166 SMCO3 TP53 TRIM17 TRIM21 TRIM8 TTC32 UBAC1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBL5 UBTD1 UBTD2 UBXN1 UBXN6 UBXN7 USP2 USP39 USP5 WDFY3 ZKSCAN4 ZNF26	5 interacting genes: APP IPO11 MEOX1 MEOX2 TRIM39
Entrez ID		56658	84812
HPRD ID		09298	07296
Ensembl ID		ENSG00000204599	ENSG00000115556
Uniprot IDs		A0A024RCP5 A0A024RCR1 Q9HCM9	C9JEA7 Q9BRC7
PDB IDs		2DID 2DIF 2ECJ
Enriched GO Terms of Interacting Partners?
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