NPDC1 and CPT1A

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		NPDC1	CPT1A
Description		neural proliferation, differentiation and control 1	carnitine palmitoyltransferase 1A
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Mitochondrion Mitochondrial Outer Membrane Membrane Integral Component Of Mitochondrial Outer Membrane
	Molecular Function	Protein Binding	Carnitine O-palmitoyltransferase Activity Identical Protein Binding Palmitoleoyltransferase Activity
	Biological Process		Long-chain Fatty Acid Metabolic Process Glucose Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Triglyceride Metabolic Process Carnitine Shuttle Response To Xenobiotic Stimulus Carnitine Metabolic Process Regulation Of Lipid Storage Response To Organic Cyclic Compound Epithelial Cell Differentiation Response To Nutrient Levels Positive Regulation Of Fatty Acid Beta-oxidation Eating Behavior Response To Alkaloid Response To Ethanol Response To Antibiotic Regulation Of Insulin Secretion Cellular Response To Fatty Acid Liver Regeneration Response To Tetrachloromethane
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	RORA activates gene expression PPARA activates gene expression Carnitine metabolism Signaling by Retinoic Acid
Drugs			Levocarnitine Glyburide Perhexiline
Diseases
GWAS		Lymphocyte counts ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) White blood cell count ( 32888494 27863252)	Apolipoprotein A1 levels ( 32203549) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) HDL cholesterol levels ( 32203549) Lipid metabolism phenotypes ( 22286219) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Obesity-related traits ( 23251661) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Triglyceride levels ( 32203549 32154731) Urate levels ( 31578528)
Interacting Genes		41 interacting genes: C3orf52 CCND1 CCND2 CCND3 CDK2 CPT1A CYSRT1 E2F1 EMD FHL5 HINFP HNRNPK KHDRBS2 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP4-1 KRTAP4-12 KRTAP4-4 KRTAP5-9 KRTAP9-3 MADD MAL MDFI MS4A13 NBPF19 NOTCH2NLA PLSCR1 RBMY1F RBMY1J TFDP1	8 interacting genes: BCL2 CLIC1 CYBA HSPA5 KBTBD7 NPDC1 NR4A1 UBC
Entrez ID		56654	1374
HPRD ID		12048	02755
Ensembl ID		ENSG00000107281	ENSG00000110090
Uniprot IDs		Q9NQX5	A0A024R5F4 B2RAQ8 P50416 Q8WZ48
PDB IDs			2LE3
Enriched GO Terms of Interacting Partners?
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