PSEN1 and APBA1

  • Number of citations of the paper that reports this interaction (PubMedID 12196555)
  • 40
  • Data Source:
  • HPRD (in vitro)

PSEN1

APBA1

Description presenilin 1 amyloid beta precursor protein binding family A member 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cognitive ability ( 29186694)
  • Cognitive ability (MTAG) ( 29186694)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Extremely high intelligence ( 29520040)
  • Intelligence ( 28530673)
  • Intelligence (MTAG) ( 29326435)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Refractive error ( 32231278)
Interacting Genes 98 interacting genes: ACTN1 AP1M2 APBA1 APH1A APH1B APOE APP BACE1 BCL2 BCL2L1 CASP1 CASP3 CASP4 CASP6 CASP7 CASP8 CDH1 CDK5 CFL1 CIB1 CKB CTNNA1 CTNNB1 CTNND1 CTNND2 CYP2C18 CYP2C8 DCT DLL1 DOCK3 ECSIT EFHD1 EFNB2 ENSA EPB41L3 ERN1 ETFA FBXL12 FBXW7 FGF13 FLNA FLNB GAPDH GCDH GDI1 GFAP GSK3B GSTZ1 HERPUD1 HMGB1 ICAM5 ITSN2 JUP KANK2 KCNIP3 KCNIP4 LRRC74A MAPK9 MAPT METTL2B MTCH1 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 OXCT1 PDCD4 PIK3R1 PKP4 PRAM1 PRDX2 PRKACA PRKCZ PSENEN PSMA5 PSMB1 RAB11A RAB3A RAD23A RBSN RHEB RMDN3 RNF32 RYR2 SCAF11 SCN1A SLC10A6 SNUPN ST13 STAMBPL1 TCF7L2 TDP2 TUBA1B UBQLN1 UMPS YME1L1 17 interacting genes: APP ARF3 ARF4 CACNA1B CASK CCS CNTNAP3 CNTNAP4 HTR2C KCNJ12 KIF17 LIN7B NOTCH1 NRXN1 PSEN1 STX1A STXBP1
Entrez ID 5663 320
HPRD ID 00087 03879
Ensembl ID ENSG00000080815 ENSG00000107282
Uniprot IDs A0A024R6A3 A0A0S2Z4D2 P49768 Q02410
PDB IDs 2KR6 4UIS 5A63 5FN2 5FN3 5FN4 5FN5 6IDF 6IYC 6LQG 6LR4 7C9I 7D8X 1AQC 1U37 1U38 1U39 1U3B 1X11 1X45 1Y7N
Enriched GO Terms of Interacting Partners?
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