PRSS8 and ATF7IP

Number of citations of the paper that reports this interaction (PubMedID 15231748)
99

Data Source:
HPRD (two hybrid)

		PRSS8	ATF7IP
Description		serine protease 8	activating transcription factor 7 interacting protein
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Exosome	Nucleus Nucleoplasm Transcription Regulator Complex Cytosol Nuclear Body
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Serine-type Peptidase Activity Sodium Channel Regulator Activity	Transcription Corepressor Activity Protein Binding
	Biological Process	Proteolysis Positive Regulation Of Sodium Ion Transport	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Protein Stabilization Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly
Pathways		Formation of the cornified envelope	PKMTs methylate histone lysines
Drugs		1-[4-(hydroxymethyl)phenyl]guanidine
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756)	Breast cancer ( 24143190) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Height ( 31562340 33713608) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Leukocyte telomere length ( 32109421) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		3 interacting genes: ATF7IP HNRNPLL SLC13A1	70 interacting genes: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CREBBP CSPG4 DISC1 DMTF1 DNM2 EHMT2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO2 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A
Entrez ID		5652	55729
HPRD ID		02895	09811
Ensembl ID		ENSG00000052344	ENSG00000171681
Uniprot IDs		Q16651	A0A024RAY1 B3KNI7 B3KQF8 Q6VMQ6
PDB IDs		3DFJ 3DFL 3E0N 3E0P 3E16 3E1X 3FVF 3GYL 3GYM	2RPQ
Enriched GO Terms of Interacting Partners?
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