PRPH and DES

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRPH	DES
Description		peripherin	desmin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Intermediate Filament Membrane Axon Perikaryon Type III Intermediate Filament Extracellular Exosome	Nucleus Cytosol Intermediate Filament Fascia Adherens Intercalated Disc Z Disc Neuromuscular Junction Sarcolemma Intermediate Filament Cytoskeleton Extracellular Exosome Cardiac Myofibril
	Molecular Function	Structural Molecule Activity Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein Binding Identical Protein Binding
	Biological Process	Intermediate Filament Cytoskeleton Organization	Muscle Contraction Cytoskeleton Organization Regulation Of Heart Contraction Intermediate Filament Organization
Pathways			Striated Muscle Contraction
Drugs
Diseases
GWAS		Prostate cancer ( 21743467) Sural nerve amplitude potential ( 30992453)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Resting heart rate ( 27798624)
Interacting Genes		36 interacting genes: CDC37 CT55 DDX6 DES FCHO1 INCA1 KIFC3 KRT14 KRT15 KRT16 KRT20 KRT24 KRT27 KRT31 KRT6A KRT75 LCA5L LENG1 LMNB1 LNX1 MAGOHB MYO5A NXF1 PIAS2 PPP1R13B PPP1R18 PRKAA2 PRPH2 PSMA1 TCEA2 TCP10L TTC23 VIM ZC4H2 ZMAT2 ZNF572	62 interacting genes: ATIC AURKB B4GALT2 BAG5 BRCA1 C1orf216 CAPN1 CLIP4 CRYAB CT55 CWF19L2 DDX10 DDX6 DSP DUX1 DUX4 EHHADH ENO1 GOLGA6L9 HSPB1 ITSN1 KRT13 KRT15 KRT20 KRT33B KRT37 KRT75 LBX1 LENG1 LMO4 LONRF3 M1AP MAPKAPK2 NEB NEFL NEK6 PIAS2 PIH1D2 PKD1 PLEKHA5 POLR2G PPL PPP1R18 PRPH RNF4 ROCK1 S100A1 S100B SHBG SNAPIN SPTAN1 SYNC SYNM TCEA2 TFIP11 TRIM55 TRIM63 TRIM7 UBE2I VIM YES1 ZMYM5
Entrez ID		5630	1674
HPRD ID		01365	00514
Ensembl ID		ENSG00000135406	ENSG00000175084
Uniprot IDs		B3KWQ6 P41219	P17661 Q53SB5
PDB IDs
Enriched GO Terms of Interacting Partners?
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