PRODH and SEPTIN5

		PRODH	SEPTIN5
Description		proline dehydrogenase 1	septin 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Intracellular Membrane-bounded Organelle	Plasma Membrane Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Septin Complex Cell Division Site
	Molecular Function	Proline Dehydrogenase Activity FAD Binding	GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity
	Biological Process	Proline Metabolic Process Proline Catabolic Process Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Proline Catabolic Process To Glutamate Positive Regulation Of Cell Death 4-hydroxyproline Catabolic Process	Synaptic Vesicle Targeting Regulation Of Exocytosis Adult Behavior Cellular Protein Localization Social Behavior Cytoskeleton-dependent Cytokinesis Regulation Of Synaptic Vesicle Exocytosis
Pathways		Proline catabolism
Drugs		Proline
Diseases
GWAS		Amino acid levels ( 26068415) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Metabolic traits ( 21886157) Metabolite levels ( 31628463) Neutrophil count ( 32888494) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Plasma free proline levels ( 30659259) Platelet count ( 32888494) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 33031748 25569235) White blood cell count ( 32888494)
Interacting Genes		7 interacting genes: GGT3P GSC2 ITM2C RANBP1 SEPTIN5 SKIV2L TBX1	24 interacting genes: APP CDK5R1 DDIT4L KAT7 KIDINS220 LSM8 MAGEA2 MAGEA2B MAPK6 MYOG PFN2 PLEKHF2 PRKN PRODH SEPTIN1 SEPTIN11 SEPTIN12 SEPTIN2 SEPTIN4 SEPTIN7 SEPTIN8 SPG21 STX1A STX4
Entrez ID		5625	5413
HPRD ID		08433	04100
Ensembl ID		ENSG00000100033	ENSG00000184702
Uniprot IDs		O43272	Q99719 X5DNA9
PDB IDs
Enriched GO Terms of Interacting Partners?
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