BARX1 and RRM2

		BARX1	RRM2
Description		BARX homeobox 1	ribonucleotide reductase regulatory subunit M2
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GO Annotations	Cellular Component	Chromatin Nucleus	Cytosol Ribonucleoside-diphosphate Reductase Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity	Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor Protein Binding Ferric Iron Binding Protein Homodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cell-cell Signaling Anterior/posterior Pattern Specification Negative Regulation Of Wnt Signaling Pathway Epithelial Cell Differentiation Spleen Development Digestive System Development	Blastocyst Development DNA Replication Deoxyribonucleotide Biosynthetic Process Protein Heterotetramerization
Pathways			Interconversion of nucleotide di- and triphosphates G1/S-Specific Transcription Transcriptional Regulation by E2F6
Drugs			Cladribine Imexon Gallium nitrate Motexafin gadolinium GTI 2040
Diseases
GWAS		Barrett's esophagus ( 24121790) Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined) ( 24121790) Esophageal adenocarcinoma ( 24121790) Heel bone mineral density ( 28869591) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Parkinson's disease ( 26227905) Serum folate levels ( 29953918)	Kidney function decline traits ( 25493955) Prostate cancer ( 23535732)
Interacting Genes		6 interacting genes: CYP17A1 HOXD9 MAPK6 RPS6KA3 RRM2 UBC	19 interacting genes: ASAP2 BARX1 CDH1 CDK1 DNM1L GCG ITSN2 KAT5 LAPTM4A LPIN1 MGAT4A NPBWR2 PLK3 RRM1 RRM2B SDCBP ST3GAL3 TAF1B TP53
Entrez ID		56033	6241
HPRD ID		16017	01587
Ensembl ID		ENSG00000131668	ENSG00000171848
Uniprot IDs		Q9HBU1	P31350
PDB IDs		2DMT	2UW2 3OLJ 3VPM 3VPN 3VPO
Enriched GO Terms of Interacting Partners?
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