NSFL1C and NGLY1

Number of citations of the paper that reports this interaction (PubMedID 16807242)
33

Data Source:
BioGRID (pull down)

		NSFL1C	NGLY1
Description		NSFL1 cofactor	N-glycanase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Golgi Stack Cytosol Plasma Membrane Spindle Pole Centrosome Intermediate Filament Cytoskeleton VCP-NSFL1C Complex	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Phospholipid Binding Ubiquitin Binding ATPase Binding	Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine Amidase Activity Protein Binding Metal Ion Binding
	Biological Process	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Golgi Organization Nuclear Membrane Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome	Protein Folding Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Glycoprotein Catabolic Process Protein Deglycosylation ER-associated Misfolded Protein Catabolic Process
Pathways		RHOH GTPase cycle	N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Drugs
Diseases
GWAS
Interacting Genes		17 interacting genes: ANP32A CDK1 DBI FAM32A FASTKD5 GLMN GSK3B LIPE NGLY1 PHAX PRKACA RPL22 SRP14 STX5 TARDBP UBC VCP	25 interacting genes: APP BICRAL FAF1 GJB2 GRM7 GUCD1 LIMD1 MAP3K2 NPAS2 NSFL1C OPA3 PAX5 PAX6 PROC RAD23A RAD23B SH3BP1 SRPK2 TCF12 TRAFD1 TRIM54 UBQLN1 UBXN2B VCP VMAC
Entrez ID		55968	55768
HPRD ID		09425	10118
Ensembl ID		ENSG00000088833	ENSG00000151092
Uniprot IDs		Q53FE8 Q9UNZ2	Q96IV0
PDB IDs		1SS6	2CCQ 2CM0
Enriched GO Terms of Interacting Partners?
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