RNF114 and XAF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		RNF114	XAF1
Description		ring finger protein 114	XIAP associated factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane	Nucleoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Zinc Ion Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Spermatogenesis Cell Differentiation	Apoptotic Process Response To Interferon-beta
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756) Inflammatory skin disease ( 25574825) Psoriasis ( 25903422 20953189 25574825 23143594) Psoriasis vulgaris ( 26626624) Systemic lupus erythematosus ( 24871463)
Interacting Genes		29 interacting genes: AK5 BMI1 EVI2A MAP3K1 MAPK3 RNF38 RPSA SMURF1 TRAF4 TRAF6 TRAIP TRIM52 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2U UBE2W UEVLD XAF1	18 interacting genes: AKT1 APP BIRC7 CREBBP GLS2 LRSAM1 RFC5 RNF114 RNF166 SEPHS1 TP53 TRIM21 TRIM50 TRIM54 TRIML2 UBXN2B VCP XIAP
Entrez ID		55905	54739
HPRD ID		10329	06978
Ensembl ID		ENSG00000124226	ENSG00000132530
Uniprot IDs		Q9Y508	Q6GPH4
PDB IDs			2LXW
Enriched GO Terms of Interacting Partners?
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