CENPN and TSSK3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CENPN	TSSK3
Description		centromere protein N	testis specific serine kinase 3
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleoplasm Cytosol
	Molecular Function		Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Chromosome Segregation Kinetochore Assembly	Protein Phosphorylation Spermatogenesis Cell Differentiation Intracellular Signal Transduction
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		4 interacting genes: ALKBH7 CCDC103 OSGIN1 TSSK3	67 interacting genes: ADAMTSL4 ARID5A ATP23 C15orf48 C2CD6 C9orf24 CENPN DDIT4L DRG2 ECSIT EFHC2 EYA2 FUT9 GOLGA2 GP2 IKZF3 INCA1 KRT75 KRTAP13-2 KRTAP13-3 LBX1 LHX3 LMO2 LNX1 LZTS2 MBD3L1 MEI4 MRPL28 MSX2 MYOG MYOZ3 NFKBID NME4 OIP5 PBX4 PJA1 PLEKHG4 PPP1R16A PRDM6 RBBP4 RBCK1 REL RIN3 RUSC1 SHISA6 SLAIN1 SMAD4 STAT5B SYNGAP1 TCF4 TCP10L TEPSIN TGM7 TLE5 TRIM35 TRIM50 TRIM54 TRIM9 TRIP6 UROD USP54 VGLL1 VPS52 YJU2B YPEL3 ZBTB25 ZMYND12
Entrez ID		55839	81629
HPRD ID		12528	09635
Ensembl ID		ENSG00000166451	ENSG00000162526
Uniprot IDs		Q96H22	Q96PN8
PDB IDs		6BUZ 6C0W 6EQT 6MUO 6MUP
Enriched GO Terms of Interacting Partners?
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