EAPP and TNFAIP8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EAPP	TNFAIP8
Description		E2F associated phosphoprotein	TNF alpha induced protein 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter	Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Pathways			PI Metabolism
Drugs
Diseases
GWAS		Celiac disease ( 23936387) Insulin-related traits (multivariate analysis) ( 32002517) Metabolite levels ( 23823483)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Apolipoprotein A1 levels ( 32203549) Asthma ( 31361310 31959851 32296059 31619474) Body shape index ( 34021172) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) HDL cholesterol levels in HIV infection ( 33109212) Heschl's gyrus morphology ( 25130324) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 31604244) Plantar fascial disorders ( 29534260) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271) Triglyceride levels ( 32203549 32154731) Triglycerides ( 30275531) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 28552196 34021172 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412) White blood cell count ( 32888494)
Interacting Genes		6 interacting genes: AAR2 BYSL TNFAIP3 TNFAIP8 UBE3A UBQLN4	11 interacting genes: ATN1 EAF1 EAPP INO80E LVRN MED4 PLEKHF1 PLEKHF2 PRR13 SDCBP TIFA
Entrez ID		55837	25816
HPRD ID		12631	18204
Ensembl ID		ENSG00000129518	ENSG00000145779
Uniprot IDs		Q56P03	B3KUI2 O95379
PDB IDs
Enriched GO Terms of Interacting Partners?
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