CENPJ and LYST

Number of citations of the paper that reports this interaction (PubMedID 11984006)
35

Data Source:
BioGRID (two hybrid)

		CENPJ	LYST
Description		centromere protein J	lysosomal trafficking regulator
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Microtubule Plasma Membrane Gamma-tubulin Small Complex	Cytosol Microtubule Cytoskeleton Membrane
	Molecular Function	Transcription Coactivator Activity Protein Binding Tubulin Binding Protein Kinase Binding Protein Domain Specific Binding Identical Protein Binding Gamma-tubulin Binding	Protein Binding Protein Kinase Binding
	Biological Process	Microtubule Nucleation Centriole Replication Astral Microtubule Nucleation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Centriole Replication Microtubule Polymerization Cell Division Cilium Assembly Centriole Elongation Positive Regulation Of Centriole Elongation Positive Regulation Of Establishment Of Protein Localization	Phagocytosis Lysosome Organization Protein Localization Protein Transport Leukocyte Chemotaxis Melanosome Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Mast Cell Secretory Granule Organization Natural Killer Cell Mediated Cytotoxicity Defense Response To Bacterium Defense Response To Protozoan Pigmentation Defense Response To Virus
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain AURKA Activation by TPX2
Drugs
Diseases
GWAS			Basophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Systemic lupus erythematosus ( 26502338 19838195)
Interacting Genes		16 interacting genes: ATN1 BCCIP CIC CREBBP EPB41 FBXO7 GFI1B LAG3 LYST MTDH SHANK3 STAT5A STAT5B TUBG1 YWHAG YWHAZ	24 interacting genes: ATN1 CALM1 CELF4 CENPJ CNTROB CSNK2B DNAJC14 EFS ESRRA ESS2 HGS HNRNPM KPNB1 MED12 MRPL17 MRPS31 NCDN PCBP4 TNNI3 VTA1 YWHAB YWHAQ YWHAZ ZNF521
Entrez ID		55835	1130
HPRD ID		09876	06060
Ensembl ID		ENSG00000151849	ENSG00000143669
Uniprot IDs		A8K8P1 F6VUX8 Q9HC77	Q99698
PDB IDs		5EIB 5ITZ
Enriched GO Terms of Interacting Partners?
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