VPS11 and RILP

Number of citations of the paper that reports this interaction (PubMedID 25445562)
23

Data Source:
BioGRID (pull down)

		VPS11	RILP
Description		VPS11 core subunit of CORVET and HOPS complexes	Rab interacting lysosomal protein
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Endocytic Vesicle HOPS Complex Late Endosome Membrane	Cytoplasm Lysosome Lysosomal Membrane Late Endosome Cytosol Phagocytic Vesicle Membrane Late Endosome Membrane Protein-containing Complex Ciliary Basal Body
	Molecular Function	Nucleotide Binding Protein Binding Protein Domain Specific Binding Syntaxin Binding Protein-macromolecule Adaptor Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Small GTPase Binding Protein Dimerization Activity Dynein Light Intermediate Chain Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Autophagy Endosome Organization Vacuole Organization Endosome To Lysosome Transport Protein Ubiquitination Regulation Of Protein Stability Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Endosomal Vesicle Fusion Organelle Fusion Regulation Of Organelle Assembly Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Early Endosome To Late Endosome Transport	Endosome To Lysosome Transport Regulation Of Multivesicular Body Size Protein Transport Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Protein Catabolic Process Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Cilium Assembly Intralumenal Vesicle Formation
Pathways			MHC class II antigen presentation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 29273807) Coronary artery disease ( 29212778 33020668) HDL cholesterol levels ( 32203549) Plateletcrit ( 32888494)
Interacting Genes		38 interacting genes: ALG9 BCAR1 BMI1 ECPAS EZR FUT1 GGA3 KDM1A KRTAP10-3 KRTAP10-8 LRSAM1 LSM1 MALL MARK3 MON1B MSN RAB7A RDX RILP RNF181 RNF26 STX1A STX6 STX7 STX8 TFAP2B TRIM32 TSG101 UBE2D2 UBE2L3 UBE2U UVRAG VPS16 VPS18 VPS33A VPS39 VPS45 WNT1	12 interacting genes: KPNA2 LDB2 RAB34 RAB7A RCHY1 SNF8 VPS11 VPS16 VPS18 VPS36 VPS39 VPS41
Entrez ID		55823	83547
HPRD ID		12258	09706
Ensembl ID		ENSG00000160695	ENSG00000167705
Uniprot IDs		A0A087WXL6 B7Z879 Q9H270	Q96NA2
PDB IDs			1YHN
Enriched GO Terms of Interacting Partners?
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