RCOR3 and PHF19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RCOR3	PHF19
Description		REST corepressor 3	PHD finger protein 19
Image
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm Transcription Regulator Complex Cytosol	Nucleus Nucleoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding	DNA Binding Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone Deacetylation Negative Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Stem Cell Population Maintenance Stem Cell Differentiation Positive Regulation Of Histone H3-K27 Methylation
Pathways			PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Plateletcrit ( 32888494)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Birth weight ( 31043758 27680694) Corneal astigmatism ( 29422769) High density lipoprotein cholesterol levels ( 29403010) Prostate-specific antigen levels ( 28139693) Pulse pressure ( 28135244 27618448) Refractive error ( 32231278)
Interacting Genes		75 interacting genes: ABI1 ANKRD11 APP BHLHB9 BORCS6 CBY2 CCDC102B CCDC106 CCHCR1 CDR2 CEP55 CEP63 CEP70 EFHC2 FAM81A FSD2 GKAP1 GLRX3 GOLGA2 GRIPAP1 GSE1 HAUS3 HMBOX1 HOOK2 HSF2BP ICA1L IKZF3 ING5 ISY1-RAB43 KDM1A KRT15 KRT18 KRT19 KRT24 KRT27 KRT31 KRT40 KRT75 LCA5 LHX3 LUZP4 LZTS2 MAGEA6 MARK3 MCC MESD MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NINL NRDE2 NUTM1 PHF19 PIH1D1 PRDM14 PTPN11 PTTG2 STN1 SUMO2 TFIP11 TRAF1 TRAF2 TRIM27 TRIM42 TRIM54 TSGA10 TULP3 TXLNA USHBP1 VAX1 YWHAQ ZNF383 ZNF688	22 interacting genes: BAG4 CDK5RAP2 CSNK2A1 DVL3 H3C1 HOMEZ HOXB5 INO80E KDM1A LZTS2 PICK1 POTEB3 RCOR3 SNIP1 SUV39H1 SUV39H2 THAP1 THAP7 TSPYL2 YTHDC1 ZNF837 ZRANB1
Entrez ID		55758	26147
HPRD ID		08338	17846
Ensembl ID		ENSG00000117625	ENSG00000119403
Uniprot IDs		Q9P2K3	A0A087X169 B7Z887 B7Z8H3 F5H8K3 Q5T6S3
PDB IDs		4CZZ	2E5Q 4BD3 6NQ3 6WAU
Enriched GO Terms of Interacting Partners?
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